46698-24-2

Usage

Uses

Used in Pharmaceutical Industry:
3-BROMO-4'-FLUOROBENZOPHENONE 97 is used as a key intermediate in the synthesis of pharmaceuticals for its ability to facilitate the creation of complex molecular structures. Its unique combination of bromine and fluorine atoms allows for specific reactivity and selectivity in chemical reactions, which is crucial for the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 3-BROMO-4'-FLUOROBENZOPHENONE 97 is utilized as an intermediate in the production of various agrochemicals. Its properties enable the synthesis of compounds that can be used in the development of pesticides, herbicides, and other agricultural chemicals, contributing to enhanced crop protection and yield.
Used in Organic Synthesis:
3-BROMO-4'-FLUOROBENZOPHENONE 97 is employed as a reagent in organic synthesis, where it aids in the formation of new chemical bonds and the modification of existing ones. Its presence in reactions can lead to the production of a wide range of organic compounds, expanding the scope of chemical research and innovation.
Used in Research and Development:
3-BROMO-4'-FLUOROBENZOPHENONE 97 plays a significant role in the research and development of new chemical compounds. Its unique structural features make it a valuable tool for exploring novel chemical reactions and pathways, paving the way for the discovery of innovative materials and substances.

InChI:InChI=1/C13H8BrFO/c14-11-3-1-2-10(8-11)13(16)9-4-6-12(15)7-5-9/h1-8H

Upstream product

• 108-36-1 1,3-dibromobenzene 
• 116332-54-8 4-fluoro-N-methoxy-N-methylbenzamide 

Downstream Products

• 247089-76-5 (3-bromophenyl)(4-fluorophenyl)methanol 
• 247089-78-7 C₁₃H₉BrClF 
• 956833-28-6 4-fluoro-3'-(3-hydroxy-3-methyl-1-butynyl)benzophenone 

Relevant academic research and scientific papers

C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF

This invention relates to a kind of C-aryl glycoside derivatives, its pharmaceutical compositions, preparation methods, and uses thereof. The preparation method comprises: method 1: in a solvent, deprotecting the acetyl protecting groups of compound 1-f in the presence of a base; method 2: 1) compound 2-g reacts with via Mitsunobu reaction; 2) deprotecting the acetyl protecting groups of compound 2-f obtained from step 1; method 3: 1) compound 2-g reacts with via nucleophilic substitution reaction; 2) deprotecting the acetyl protecting groups of compound 3-f obtained from step 1. The pharmaceutical composition comprises a kind of C-aryl glycoside derivatives; it's pharmaceutically acceptable salts and/or prodrugs thereof and excipient thereof. This invention further relates to a kind of C-aryl glycoside derivatives, it's pharmaceutically acceptable salts or pharmaceutical compositions thereof for the use in preparation of a SGLT inhibitor. The C-aryl glycoside derivatives of this invention provides a new direction for the study of SGLT inhibitors.

Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors

A small library of 36 functionalized benzophenone thiosemicarbazone analogs has been prepared by chemical synthesis and evaluated for their ability to inhibit the cysteine proteases cathepsin L and cathepsin B. Inhibitors of cathepsins L and B have the potential to limit or arrest cancer metastasis. The six most active inhibitors of cathepsin L (IC50 50 > 10,000 nM). The most active analog in the series, 3-bromophenyl-2′-fluorophenyl thiosemicarbazone 1, also efficiently inhibits cell invasion of the DU-145 human prostate cancer cell line.