467221-26-7

Upstream product

• 82891-99-4 ethylene ketal of 3-nitropropanal 
• 768-60-5 4-methoxyphenylacetylen 
• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 

Downstream Products

• 1312809-31-6 2-(1-hydroxy-4-oxo-cyclohexa-2,5-dienyl)-pyran-4-one 
• 117016-27-0 2-(4-hydroxyphenyl)-4H-pyran-4-one 
• 1312809-32-7 C₁₄H₁₇NO₄ 
• 467221-39-2 (Z)-3-Amino-4-[1,3]dioxolan-2-yl-1-(4-methoxy-phenyl)-but-2-en-1-one 

Relevant academic research and scientific papers

A novel, broad-spectrum antitumor compound containing the 1-hydroxycyclohexa-2,5-dien-4-one group: The disclosure of a new antitumor pharmacophore in protoapigenone 1

The synthesis of a new compound 9 containing the 4-hydroxy-2,5- cyclohexadien-1-one system, a key elements toward elucidation of the protoapigenone 1 antitumor pharmacophore, was described. The compound showed potent in vitro antitumor potency with low mi

Studies on synthesis of a novel, broad-spectrum antitumor compound 2-(1-hydroxy-4-oxo-cyclohexa-2, 5-dienyl)-pyran-4-one

Based on the previous studies, used protoapigenone as a model, we adopted chemical synthesis methods to develop the new compounds. It was specifically named as 2-(1-hydroxy-4-oxo-2, 5-cyclohexadien-1-yl)-4H-Pyran-4-one, including a core group: 1-hydroxycy

Synthesis of pyran-4-ones from isoxazoles

A synthesis of mono-, di- and tri-substituted pyran-4-ones from isoxazoles is reported. The isoxazoles can be synthesized from readily available starting materials and undergo a reductive cleavage reaction with Mo(CO)6 to generate enamino keton