467225-75-8

Upstream product

• 77-78-1 dimethyl sulfate 
• 467225-71-4 S-ethyl bis(ethylsulfanyl)(4-isobutylphenyl)thioacetate 
• 154320-56-6 methyl 4-iso-butylbenzoate 
• 467225-66-7 2,2,2-tris(ethylsulfanyl)-1-(4-isobutylphenyl)ethanone 

Downstream Products

• 467225-79-2 S-ethyl α-(4-isobutylphenyl)thiopropionate 
• 15687-27-1 ibuprofen 

Relevant academic research and scientific papers

An interesting synthetic application of S-alkyl (aryl)bis(alkylsulfanyl)thioacetates: General procedure for the preparation of (±)-α-arylpropionic acids

Reported here is a new procedure for the synthesis of α-arylpropionic acids 1 in the racemic form, starting from derivatives of aromatic carboxylic acids 2 (i.e., esters), via 1-aryl-2,2,2-tris(alkylsulfanyl)ethanones 4-6, S-alkyl (aryl)bis(alkylsulfanyl)thioacetates 7-9, S-alkyl α-aryl-α-(alkylsulfanyl)thiopropionates 10-12 and S-alkyl α-arylthiopropionates 13-15. Each stage takes place easily and yields are always high.