46727-05-3

Upstream product

• 857419-87-5 1,3-bis-(1-methyl-pyrrol-2-yl)-acetone 
• 466645-81-8 N-allyl-N-[4-allylamino-6-(tert-butyl-dimethyl-silanyloxy)-cyclohept-2-enyl]-4-nitro-benzenesulfonamide 
• 466645-77-2 Acetic acid (1S,4S,6S)-4-[allyl-(4-nitro-benzenesulfonyl)-amino]-6-(tert-butyl-dimethyl-silanyloxy)-cyclohept-2-enyl ester 
• 466645-80-7 N-allyl-N-[6-(tert-butyl-dimethyl-silanyloxy)-4-chloro-cyclohept-2-enyl]-4-nitro-benzenesulfonamide 
• 466645-84-1 C₁₉H₄₀N₂OSi 
• 134734-52-4 (1R,4S,6S)-4-acetoxy-6-[(tert-butyldimethylsilyl)oxy]-2-cyclohepten-1-ol 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 542-05-2 acetonedicarboxylic acid 
• 468732-35-6 dihydrocuscohydrine 
• 466645-83-0 C₂₃H₄₄N₂O₅Si 
• 466645-82-9 Allyl-[(1S,4S)-4-(allyl-ethoxycarbonyl-amino)-6-(tert-butyl-dimethyl-silanyloxy)-cyclohept-2-enyl]-carbamic acid ethyl ester 
• 466645-79-4 N-allyl-N-[6-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-cyclohept-2-enyl]-4-nitro-benzenesulfonamide 

Downstream Products

• 80408-55-5 dihydrocuscohygrine 

Relevant academic research and scientific papers

Chemotaxonomy of the pantropical genus Merremia (Convolvulaceae) based on the distribution of tropane alkaloids

The occurrence and distribution of tropane and biogenetically related pyrrolidine alkaloids in 18 Merremia species of paleo-, neo-, and pantropical occurrence have been studied. The extensive GC-MS study included members of almost all sections of the genu

Total synthesis of (+)-dihydrocuscohygrine and cuscohygrine

The first enantioselective synthesis of (+)-dihydrocuscohygrine 1 and cuscohygrine 2 is presented. 1 was obtained in nine steps and 30% overall yield with a ruthenium-catalyzed tandem ring rearrangement metathesis key step starting from enantiomerically pure cycloheptene-1,3,5-triol derivative 6. The unknown absolute configuration of natural dihydrocuscohygrine 1 could be determined as (S,S)-(-). Cuscohygrine 2 was obtained by Jones oxidation of 1 in quantitative yield but unfortunately with complete epimerization.