467443-07-8

Basic information

• Product Name: 1-(2,4,5-trioxo-imidazolidin-1-yl)cyclohexanecarboxylic acid ethyl ester
• Synonyms: 1-(2,4,5-trioxo-imidazolidin-1-yl)cyclohexanecarboxylic acid ethyl ester
• CAS NO: 467443-07-8
• Molecular Weight: 268.269
• Mol File: 467443-07-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,4,5-trioxo-imidazolidin-1-yl)cyclohexanecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4,5-trioxo-imidazolidin-1-yl)cyclohexanecarboxylic acid ethyl ester(467443-07-8)
• EPA Substance Registry System: 1-(2,4,5-trioxo-imidazolidin-1-yl)cyclohexanecarboxylic acid ethyl ester(467443-07-8)

Safety Data

• Hazardous Substances Data: 467443-07-8(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 5046-73-1 1-Ureido-cyclohexanecarboxylic acid ethyl ester 
• 63203-48-5 1-amino-cyclohexanecarboxylic acid ethyl ester hydrochloride 
• 2756-85-6 1-aminocyclohexane carboxylic acid 

Downstream Products

• 702-62-5 spiro(imidazolidine-4,1'-cyclohexane)-2,5-dione 

Relevant articles and documents

Synthesis, selective aldose reductase inhibitory profile and antihyperglycaemic potential of certain parabanic acid derivatives

Synthesis and aldose reductase inhibitory profile of certain parabanic acid derivatives 1a-p is described. Also, the antihyperglycaemic potential of these compounds was studied. The most active inhibitors in this series were compounds 1 g, 1p, and 1o which showed inhibitory activity, 36.6, 90 and 91% respectively, at concentration 1 × 10-4. Their IC50 were 2 × 10-6, 7.5 × 10-8 and 5 × 10-8, respectively. Compound 1o exhibited pronounced antihyperglycaemic effect.