468055-61-0

Upstream product

• 67-56-1 methanol 
• 7217-59-6 2-Methoxybenzenethiol 
• 13920-94-0 bis(2-methoxyphenyl)disulfide 

Downstream Products

• 118617-58-6 N-<(o-methoxyphenylsulfonyl)methyl>formamide 
• 118617-63-3 1-((isocyanomethyl)sulfonyl)-2-methoxybenzene 
• 130610-67-2 C₁₀H₁₄O₂S 
• 1453071-06-1 1-((2-methoxyphenyl)sulfinyl)cyclohexanecarbonitrile 
• 871939-91-2 (E)-N-benzylidene-2-methoxybenzenesulfinamide 
• 871939-92-3 (E)-N-(2-methylpropylidene)-2-methoxybenzenesulfinamide 
• 871939-85-4 2-methoxyphenylsulfinamide 

Relevant academic research and scientific papers

Metal- And oxidant-free electrochemical synthesis of sulfinic esters from thiols and alcohols

An efficient and eco-friendly electrochemical synthesis of various sulfinic esters from thiols and alcohols via sequential S-H/S bond cleavage and double S-O bond formation under mild reaction conditions has been developed. Stoichiometric oxidants, metal catalysts, activating agents and even added bases were avoided in this method, and the only by-product generated from this reaction was dihydrogen gas which could serve as a green source of energy. Various functional groups are compatible with this green protocol which can be easily conducted on a gram-scale.

Alkyl sulfinates: Formal nucleophiles for synthesizing TosMIC analogs

Alkyl sulfinates function as formal nucleophiles in Mannich-type reactions to give sulfonyl formamides, which are readily dehydrated to the corresponding sulfonylmethyl isonitriles. The efficient, two-step synthesis provides a general route to sulfonylmethyl isonitriles from readily available methyl sulfinates or thiols. Mechanistic analysis reveals that the unusual nucleophlicity of the alkyl sulfinates arises from the in situ release of sulfinic acids.

COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES

This invention relates to novel isonitriles, including arylsulfonyl isonitriles, and methods for their synthesis. The isonitriles include a conjugated ring system. The structure is designed with the flexibility to have multiple substitution patterns. The isonitriles may be used in applications including, but not limited to, pharmaceutical compositions.

A new general method for the preparation of N-sulfonyloxaziridines

(Chemical Equation Presented) A simple procedure to obtain N-alkylsulfonyl- and N-arylsulfonyloxaziridines from the corresponding N-sulfinylimines involving a one-pot, two-step oxidation process with m-CPBA (1 equiv) and m-CPBA/KOH (1.1 equiv) is reported