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4-Bromo-N-methylpyridin-2-amine is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is characterized by the presence of a bromine atom at the 4-position, a methyl group attached to the nitrogen atom, and an amino group at the 2-position on the pyridine ring. This unique structure endows it with specific chemical properties that make it a valuable building block in the development of new drugs and therapeutic agents.

468718-65-2

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468718-65-2 Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-N-methylpyridin-2-amine is used as a synthetic intermediate for the preparation of B-[2-(Methylamino)-4-pyridinyl]boronic Acid Hydrochloride Hydrate (M227308). 4-Bromo-N-methylpyridin-2-amine is further utilized in the synthesis of novel selective thiazoleacetic acids, which act as CRTH2 antagonists. CRTH2 antagonists have potential applications in the treatment of various inflammatory and allergic diseases, such as asthma and allergic rhinitis, by targeting the chemoattractant receptor-homologous molecule expressed on Th2 cells.

Check Digit Verification of cas no

The CAS Registry Mumber 468718-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,8,7,1 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 468718-65:
(8*4)+(7*6)+(6*8)+(5*7)+(4*1)+(3*8)+(2*6)+(1*5)=202
202 % 10 = 2
So 468718-65-2 is a valid CAS Registry Number.

468718-65-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-N-methylpyridin-2-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:468718-65-2 SDS

468718-65-2Relevant academic research and scientific papers

IRAK DEGRADERS AND USES THEREOF

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Paragraph 00962; 001999-002001, (2020/06/19)

The present invention provides compounds, compositions thereof, and methods of using the same.

HETEROCYCLIC COMPOUNDS AND USES THEREOF

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Paragraph 0920-0922, (2019/04/25)

Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

IRAK DEGRADERS AND USES THEREOF

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Paragraph 4260; 4261, (2019/07/10)

The present invention provides compounds, compositions thereof, and methods of using the same.

PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL

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Paragraph 0318; 0319, (2017/06/29)

The present invention provides a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof which has an excellent NHE3 inhibitory effect: ????????[Formula 15]?????A-Y [1] wherein A represents a structure represented b

Hetarynic synthesis and chemical transformation of dihydrodipyridopyrazines

Blanchard, Stéphanie,Rodriguez, Ivan,Kuehm-Caubère, Catherine,Renard, Pierre,Pfeiffer, Bruno,Guillaumet, Gérald,Caubère, Paul

, p. 3513 - 3524 (2007/10/03)

Unprecedented dihydrodipyridopyrazines were easily obtained by hetarynic dimerization of 2-alkylamino-3-halogenopyridines in the presence of the complex base NaNH2-tBuONa. Derivatizations of the new heterocycles are described. The anticancer ac

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