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468740-43-4

468740-43-4

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  • Factory Price API 99% Insulin-like Growth Factor-1 Receptor Inhibitor 468740-43-4 GMP Manufacturer

    Cas No: 468740-43-4

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468740-43-4 Usage

Uses

BMS 536924 is an inhibitor of insulin-like growth factor receptor (IGF1R) kinase and insulin receptor. BMS 536924 was reported to have antitumor activity.

Check Digit Verification of cas no

The CAS Registry Mumber 468740-43-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,8,7,4 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 468740-43:
(8*4)+(7*6)+(6*8)+(5*7)+(4*4)+(3*0)+(2*4)+(1*3)=184
184 % 10 = 4
So 468740-43-4 is a valid CAS Registry Number.
InChI:InChI=1/C25H26ClN5O3/c1-15-11-18(31-7-9-34-10-8-31)13-20-23(15)30-24(29-20)22-19(5-6-27-25(22)33)28-14-21(32)16-3-2-4-17(26)12-16/h2-6,11-13,21,32H,7-10,14H2,1H3,(H,29,30)(H2,27,28,33)/t21-/m1/s1

468740-43-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-4-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one

1.2 Other means of identification

Product number -
Other names 4-[[(2S)-2-(3-CHLOROPHENYL)-2-HYDROXYETHYL]AMINO]-3-[7-METHYL-5-(4-MORPHOLINYL)-1H-BENZIMIDAZOL-2-YL]-2(1H)-PYRIDINONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:468740-43-4 SDS

468740-43-4Downstream Products

468740-43-4Relevant articles and documents

Discovery of a 1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity

Wittman, Mark,Carboni, Joan,Attar, Ricardo,Balasubramanian, Balu,Balimane, Praveen,Brassil, Patrick,Beaulieu, Francis,Chang, Chiehying,Clarke, Wendy,Dell, Janet,Eummer, Jeffrey,Frennesson, David,Gottardis, Marco,Greer, Ann,Hansel, Steven,Hurlburt, Warren,Jacobson, Bruce,Krishnananthan, Subramaniam,Lee, Francis Y.,Li, Aixin,Lin, Tai-An,Liu, Peiying,Ouellet, Carl,Sang, Xiaopeng,Saulnier, Mark G.,Stoffan, Karen,Sun, Yax,Velaparthi, Upender,Wong, Henry,Yang, Zheng,Zimmermann, Kurt,Zoeckler, Mary,Vyas, Dolatrai

, p. 5639 - 5643 (2007/10/03)

Compound 3 (BMS-536924), a novel small-molecule inhibitor of the insulin-like growth factor receptor kinase with equal potency against the insulin receptor is described. The in vitro and in vivo biological activity of this interesting compound is also rep

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