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(1R,2S)-2-Ethylamino-1,2-diphenyl-ethanol is a chiral organic compound with the molecular formula C16H19NO. It is a secondary amine derivative, featuring a 1,2-diphenyl-ethanol backbone with an ethylamine substituent at the 2-position. The compound exhibits two stereocenters, with the R-configuration at the 1-position and the S-configuration at the 2-position. This chirality is crucial for its potential applications in the synthesis of pharmaceuticals and other chiral molecules, as the spatial arrangement of atoms can significantly influence biological activity. The compound is also known for its potential use in the preparation of enantiomerically pure compounds, which is valuable in the field of asymmetric synthesis.

46878-59-5

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46878-59-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 46878-59-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,6,8,7 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 46878-59:
(7*4)+(6*6)+(5*8)+(4*7)+(3*8)+(2*5)+(1*9)=175
175 % 10 = 5
So 46878-59-5 is a valid CAS Registry Number.

46878-59-5Relevant academic research and scientific papers

Easily accessible chiral amino-phosphinite ligands for highly enantioselective palladium-mediated allylic alkylation

Chen, Guoshu,Li, Xin,Zhang, Haile,Gong, Liuzhu,Mi, Aiqiao,Cui, Xin,Jiang, Yaozhong,Choi, Michael C.K.,Chan, Albert S.C.

, p. 809 - 813 (2002)

Palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with the dimethyl malonate-BSA-LiOAc system has been successfully carried out in the presence of easily prepared new chiral amino-phosphinite ligands such as 3b and 3c to

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