4688-64-6Relevant academic research and scientific papers
Enantioselective synthesis of azaflavanones using organocatalytic 6-endo aza-Michael addition
Cheng, Shuanghua,Zhao, Lili,Yu, Shouyun
supporting information, p. 982 - 986 (2014/04/03)
A method to prepare highly enantioenriched azaflavanones using an organocatalytic 6-endo aza-Michael addition has been described. A variety of 2-aryl-, 2-vinyl- and 2-methylazaflavanones were prepared in good yields (53-84%) and excellent enantioselectivities (97.6:2.4 to 99.3:0.7 er).
SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE OF THE SAME AS MEDICAMENTS, AND MEDICAMENT CONTAINING SUCH COMPOUNDS
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Page/Page column 50, (2008/06/13)
The invention relates to compounds of formula I wherein R1 to R9 have the designations cited in the patent claims. Medicaments containing this type of compound can be used in the prevention or treatment of various illnesses. Said compounds can be used, inter alia, for renal diseases such as acute or chronic kidney failure, for disturbances of the biliary function, for respiratory disturbances such as snoring or sleep apnoea, or for apoplexy.
Modified aminoacids, pharmaceuticals containing these compounds and method for their production
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Example A16a), (2008/06/13)
The present invention relates to modified amino acids of general formula wherein A, Z, X, n, m, R, R2, R3, R4and R11are defined as in claims 1 to 5, their tautomers, their diastereomers, their enantiomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them as well as their use for the production and purification of antibodies and as labelled compounds in RIA- and ELISA assays and as diagnostic or analytical aids in neurotransmitter research.
Synthesis of 2,3-disubstituted 4-oxoquinolines and 3-substituted fused 4-oxoquinolines
Alkhathlan, Hamad Z.,Al-Farhan, Khalid A.
, p. 641 - 655 (2007/10/03)
Seven 2,3-disubstituted 4-oxoquinolines were prepared via two methods. In the first one 2,3-disubstituted 4-oxoquinolines were prepared via the condensation of 2-amino-α-cyanoacetophenone with substituted phthalic anhydrides, while in the second method the fused isoindolo[2,1-a]quinolines and pyrrolo[1,2-a]quinolines were first prepared and then converted to 4-oxoquinolines. X-Ray crystal structure analysis of ethyl 2-[3-cyano-4-oxo-2-quinolyl]benzoate is reported.
