4693-31-6

Usage

Type

Chemical compound

Derivative of

Resorcinol (a dihydroxybenzene)

Applications

a. Skincare products
b. Pharmaceuticals
c. Hair dye ingredient
d. Rubber manufacturing
e. Organic synthesis
f. Polymer chemistry

Properties

a. Antiseptic
b. Antioxidant

Safety precautions

Handle with caution, as it can be toxic if ingested or inhaled in large quantities.

Upstream product

• 10342-59-3 1-nitro-4-propyl-benzene 
• 79-03-8 propionyl chloride 
• 150-78-7 1,4-dimethoxybezene 
• 123-38-6 propionaldehyde 
• 637-88-7 1,4-Cyclohexanedione 
• 645-56-7 4-n-Propylphenol 
• 7647-01-0 hydrogenchloride 
• 938-46-5 2',5'-dihydroxypropiophenone 
• 7664-93-9 sulfuric acid 
• 5905-48-6 dipropylcadmium 
• 106-51-4 p-benzoquinone 
• 123-31-9 hydroquinone 

Downstream Products

• 55811-48-8 2-n-propyl-1,4-benzoquinone 
• 38843-85-5 2,5-dimethoxy-1-n-propylbenzene 
• 13183-89-6 2-Propyl-5-sulfo-hydrochinon 
• 873411-92-8 1-(2-hydroxy-5-methoxy-4-propyl-phenyl)-ethanone 
• 198203-80-4 5-propyl-benzene-1,2,4-triol 

Relevant academic research and scientific papers

Experimental and semiemprical studies of chemical reactivity of dialkylcadmium reagents addition to α,β-enones

Experimental and semiempirical calculations were carried out to study the reactivity of dialkylcadmium reagents addition to α,β-enones. It was demonstrated that α,β-enone such as benzoquinone with low lying LUMO energy reacts via single electron transfer (SET) mechanism with the formation of the 1,2 or 1,4-type alkyl addition product depending on the reaction temperature and substrate structure. Site and chemoselectivity in unsymmetrical benzoquinone derivatives are determined by the stability of the cadmium coordinated semienone complex intermediates and the carbon spin densities of these reactive species respectively. On the other hand, by increasing the LUMO energy of α,β-enone system, the reaction mechanism changes from SET to polar addition affording the 1,4-type alkyl addition product. The establishment of a correlation scale between substrate LUMO energies and reaction mechanism presented in this article will be discussed.

Evidence for single electron transfer (SET) pathway in the reaction of primary alkylcadmium reagents with p-benzoquinone

The reaction of primary alkylcadmium reagents with p-benzoquinone at various conditions was studied. On the basis of our results, reaction proceeds through a SET mechanism that forms loose and tight intermediates, which produce quinole (1) and substituted hydroquinone (2). In both cases, hydroquinone (3) is obtained in different yields.

Benzisoxazole-derived antidiabetic compounds

The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.

A Convenient Synthesis of 2-Alkylated 1,4-Benzenediols

Reaction of 1,4-cyclohexanedione with a variety of aldehydes in the presence of metal halides generated the 2-alkylated 1,4-benzenediols in good yields without any aromatic by-products.