469862-45-1

Basic information

• Product Name: 3-(3-furyl)-6-phenyl-2H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione
• Synonyms: 3-(3-furyl)-6-phenyl-2H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione
• CAS NO: 469862-45-1
• Molecular Weight: 278.267
• Mol File: 469862-45-1.mol

Chemical Properties

• CAS DataBase Reference: 3-(3-furyl)-6-phenyl-2H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-furyl)-6-phenyl-2H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione(469862-45-1)
• EPA Substance Registry System: 3-(3-furyl)-6-phenyl-2H,5H-pyrrolo[3,4-c]pyrrole-1,4-dione(469862-45-1)

Safety Data

• Hazardous Substances Data: 469862-45-1(Hazardous Substances Data)

Upstream product

• 488-93-7 3-Furoic acid 
• 10539-50-1 diethyl 2-benzoylsuccinate 
• 30078-65-0 3-furylnitrile 
• 105194-22-7 2,3-dihydro-2-oxo 5-phenyl-1H-pyrrole-4-carboxylic acid ethyl ester 

Relevant articles and documents

Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 1: The search for alkenyl-DPPs. Unsaturated nitriles in standard DPP syntheses: A novel cyclopenta[c]pyrrolone chromophore

Reactions of the anion of ethyl 4,5-dihydro-5-oxo-2-phenylpyrrole-3-carboxylate with the Diels-Alder adducts of acrylonitrile and various dienes rarely yield the expected DPP derivatives. The reaction with cyclohex-3-enecarbonitrile provides a noteworthy exception: thermolysis of the resulting cyclohexenyl-DPP gives butadiene and impure 3-ethenyl-6-phenyl-DPP, the latter being thermally unstable. Michael additions predominate when the above anion reacts with α,β-unsaturated nitriles: acrylonitrile and methacrylonitrile give 4,4-bis(cyanoethyl) and 4,4-bis(2-cyanopropyl) derivatives, and cinnamonitrile, substituted cinnamonitriles and 3-(2-thienyl)acrylonitrile give deep red 3-aryl-5-cyano-4-hydroxy-2H-cyclopenta[c]pyrrol-1-ones. These ambident nucleophiles may undergo N- and either O- or C-alkylation according to the alkylating agent used.