470-16-6

Basic information

• Product Name: leucrose (5-O-α-D-glucopyranosyl-β-D-fructopyranose)
• CAS NO: 470-16-6
• Molecular Weight: 342.3
• Mol File: 470-16-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: leucrose (5-O-α-D-glucopyranosyl-β-D-fructopyranose)(CAS DataBase Reference)
• NIST Chemistry Reference: leucrose (5-O-α-D-glucopyranosyl-β-D-fructopyranose)(470-16-6)
• EPA Substance Registry System: leucrose (5-O-α-D-glucopyranosyl-β-D-fructopyranose)(470-16-6)

Safety Data

• Hazardous Substances Data: 470-16-6(Hazardous Substances Data)

Upstream product

• 59-92-7 levodopa 
• 57-50-1 Sucrose 
• 124040-50-2 benzyl 1,3,4-tri-O-benzoyl-β-D-fructopyranoside 
• 89025-46-7 2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl fluoride 
• 41847-61-4 (3S,4S,5R)-2-(hydroxymethyl)tetrahydropyran-2,3,4,5-tetrol 
• 921-60-8 L-glucose 
• 56180-94-0 α-acarbose 
• 124040-55-7 Benzyl-1,3,4-tri-O-benzoyl-5-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-fructopyranosid 

Downstream Products

• 1551576-98-7 2-[(1'R,2'S,3'R)-3'-(α-D-glucopyranosyloxy)-1',2',4'-trihydroxybutyl]quinoxaline 
• 1462942-91-1 4-[(1'R,2'S,3'R)-3'-(α-D-glucopyranosyloxy)-1',2',4'-trihydroxybutyl]-2-methylimidazole 
• 1462942-88-6 4-[(1'R,2'S,3'R)-3'-(α-D-glucopyranosyloxy)-1',2',4'-trihydroxybutyl]-imidazole 

Relevant articles and documents

Synthesis of acarbose analogues by transglycosylation reactions of Leuconostoc mesenteroides B-512FMC and B-742CB dextransucrases.

Two new acarbose analogues were synthesized by the reaction of acarbose with sucrose and dextransucrases from Leuconostoc mesenteroides B-512FMC and B-742CB. The major products for each reaction were subjected to yeast fermentation, and then separated and

Alternansucrase acceptor reactions with D-tagatose and L-glucose

Alternansucrase (EC 2.4.1.140) is a d-glucansucrase that synthesizes an alternating α-(1→3), (1→6)-linked d-glucan from sucrose. It also synthesizes oligosaccharides via d-glucopyranosyl transfer to various acceptor sugars. Two of the more efficient monosaccharide acceptors are d-tagatose and l-glucose. In the presence of d-tagatose, alternansucrase produced the disaccharide α-d-glucopyranosyl-(1→1)-β-d-tagatopyranose via glucosyl transfer. This disaccharide is analogous to trehalulose. We were unable to isolate a disaccharide product from l-glucose, but the trisaccharide α-d-glucopyranosyl-(1→6)-α-d-glucopyranosyl-(1→4) -l-glucose was isolated and identified. This is analogous to panose, one of the structural units of pullulan, in which the reducing-end d-glucose residue has been replaced by its l-enantiomer. The putative l-glucose disaccharide product, produced by glucoamylase hydrolysis of the trisaccharide, was found to be an acceptor for alternansucrase. The disaccharide, α-d-glucopyranosyl- (1→4)-l-glucose, was a better acceptor than maltose, previously the best known acceptor for alternansucrase. A structure comparison of α-d-glucopyranosyl-(1→4)-l-glucose and maltose was performed through computer modeling to identify common features, which may be important in acceptor affinity by alternansucrase.