4703-03-1

Basic information

• Product Name: 2-((((benzyloxy)carbonyl)amino)oxy)-2-phenylacetic acid
• Synonyms: 2-((((benzyloxy)carbonyl)amino)oxy)-2-phenylacetic acid
• CAS NO: 4703-03-1
• Molecular Weight: 301.299
• Mol File: 4703-03-1.mol

Chemical Properties

• CAS DataBase Reference: 2-((((benzyloxy)carbonyl)amino)oxy)-2-phenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((((benzyloxy)carbonyl)amino)oxy)-2-phenylacetic acid(4703-03-1)
• EPA Substance Registry System: 2-((((benzyloxy)carbonyl)amino)oxy)-2-phenylacetic acid(4703-03-1)

Safety Data

• Hazardous Substances Data: 4703-03-1(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 4702-99-2 2-(aminooxy)-2-phenylacetic acid hydrochloride 
• 4585-46-0 α--phenylessigsaeure 
• 4870-65-9 2-bromophenylacetic acid 

Relevant articles and documents

Amidyl Radicals by Oxidation of α-Amido-oxy Acids: Transition-Metal-Free Amidofluorination of Unactivated Alkenes

A three-component transition-metal-free amidofluorination of unactivated alkenes and styrenes is presented. α-Amido-oxy acids are introduced as efficient and easily accessible amidyl radical precursors that are oxidized by a photoexcited organic sensitizer (Mes-Acr-Me) to the corresponding carboxyl radical. Sequential CO2 and aldehyde/ketone fragmentation leads to an N-centered radical that adds to an alkene. Commercial Selectfluor is used to trap the adduct radical through fluorine-atom transfer. The transformation features by high functional-group tolerance, broad substrate scope, and practical mild conditions. Mechanistic studies support the radical nature of the cascade.