470461-18-8

Upstream product

• 90553-67-6 1-(3,4-dimethoxy-benzylidene)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester 
• 22185-86-0 ethyl 1-(3',4'-dimethoxybenzylidene)-3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinecarboxylate 

Downstream Products

• 154490-65-0 N-1-<2-(3,4-dimethoxyphenyl)-6,7-dimethoxynaphthyl>ethylcarbamate 
• 302331-51-7 ethyl 2-(3,4-dimethoxyphenyl)-6,7-dimethoxynaphthalen-1-yl(methyl)carbamate 
• 102012-82-8 1-amino-6,7-dimethoxy-2-(3,4-dimethoxyphenyl)naphthalene 
• 114253-63-3 O-methyl-6-oxofagaronine 
• 470461-20-2 [(Z)-2-(3,4-Dimethoxy-phenyl)-1-(4,5-dimethoxy-2-vinyl-phenyl)-vinyl]-methyl-carbamic acid ethyl ester 
• 199292-64-3 6,7-dimethoxy-3-[2-(2',2-dimethoxyethyl)-4,5-dimethoxyphenyl]-2-methyl-1(2H)-isoquinolinone 
• 125455-89-2 3-(2-vinyl-4,5-dimethoxyphenyl)-6,7-dimethoxy-2-methyl-1,2-dihydroisoquinoline-1-one 

Relevant academic research and scientific papers

(Z)-Ethyl 2-phenyl-1-(2-vinylphenyl)vinylcarbamates. Part 1: Synthesis and preliminary studies on their divergent transformation into benzo[c] phenanthridines and 2-phenyl-1,4-naphthoquinones

Treatment of N-carbethoxy-1-benzylideneisoquinolines with LDA gives N-ethoxycarbonyl-1-amino-1-(2-vinylphenyl)-2-phenylethylenes, which can easily be transformed into N-carbethoxy-1-amino-2-phenylnaphthalenes. Bischler-Napieralski reaction of these latter

A new route to 3-(2-vinylphenyl)-2-methyl-2H-isoquinolin-1-ones and benzo[c]phenanthridines: Total synthesis of fagaronine

Treatment of N-carbethoxy-1-benzylideneisoquinolines with LDA gives N-ethoxycarbonyl-1-amino-1-(2-vinylphenyl)-2-phenylethylenes, which can be transformed into 3-(2-vinylphenyl)-2-methyl-2H-isoquinolin-1-ones by Bischler-Napieralski reactions, and thence

A novel C-N cleavage in isoquinolines allowing the first direct transformation of 1-benzylisoquinolines into benzo[c]phenanthridines and a new route to 2-phenyl-1,4-naphthoquinones

Treatment of N-carbethoxy-1-benzylideneisoquinolines with LDA gives N-ethoxycarbonyl-1-amino-1-(2-vinylphenyl)-2-phenylethylenes, which can easily be transformed into N-carbethoxy-1-amino-2-phenyl-naphthalenes. Bichler-Napieralski reaction of these latter compounds affords the corresponding benzo[c]-phenanthridines, while their hydrolysis and subsequent oxidation constitutes a route to 2-phenyl-1,4-naphthoquinones. (C) 2000 Elsevier Science Ltd.