4707-88-4Relevant academic research and scientific papers
Synthesis and characterization of flame-retardant polyurethane elastomers using phosphorus-containing chain extender
Xu, Wenzong,Li, Wenxiu,Ren, Mingyuan,Yin, Jianguo
, p. 5683 - 5685 (2013)
Phenylphosphonic diamine was synthesized from phenylphosphonic dichloride and characterized by Fourier transform infrared spectroscopy and nuclear magnetic resonance. Then phenylphosphonic diamine was used to prepare a series of phosphorus containing poly
Phosphonamidates are the first phosphorus-based zinc binding motif to show inhibition of β-class carbonic anhydrases from bacteria, fungi, and protozoa
Alissa, Siham A.,Alghulikah, Hanan A.,Alothman, Zeid A.,Osman, Sameh M.,Del Prete, Sonia,Capasso, Clemente,Nocentini, Alessio,Supuran, Claudiu T.
, p. 59 - 64 (2019/11/11)
A primary strategy to combat antimicrobial resistance is the identification of novel therapeutic targets and anti-infectives with alternative mechanisms of action. The inhibition of the metalloenzymes carbonic anhydrases (CAs, EC 4.2.1.1) from pathogens (
Phosphorus versus Sulfur: Discovery of Benzenephosphonamidates as Versatile Sulfonamide-Mimic Chemotypes Acting as Carbonic Anhydrase Inhibitors
Nocentini, Alessio,Gratteri, Paola,Supuran, Claudiu T.
supporting information, p. 1188 - 1192 (2019/01/04)
The first zinc-binding group (ZBG) to have been identified as inhibitor of the metallo-enzymes carbonic anhydrases (CA, EC 4.2.1.1) was the sulfonamide. From then on several classes of zinc-binders have been described. This work reports the benzenephospon
The reaction of ammonia-chloramine mixtures with phosphorus-phosphorus bonds
Frazier, Stephen E.,Sisler, Harry H.
, p. 925 - 928 (2007/10/05)
The reactions of ammonia-chloramine mixtures with tetramethyldiphosphine, tetraethyldiphosphine, tetraphenyldiphosphine, and tetraphenylcyclotetraphosphine have been shown to result in the fission of the phosphorus-phosphorus bonds and in the formation of the same products as would be expected from the reaction of ammonia-chloramine mixtures with the corresponding mono- or dihalophosphines. The previously postulated but not isolated compounds [(C6H5)2P(NH2)2]Cl and [(C6H5)P(NH2)3]Cl were obtained. It is postulated that the initial products of the P-P bond fission are R2PCl and R2PNH2. It was also shown that dimethyldiaminophosphonium chloride reacts with PCl5 to yield (CH3)2Cl4P3N3. The mode of formation and the infrared spectrum indicate that this product is a phosphonitrilic cyclic trimer in which both methyl groups are on the same phosphorus atom.
