470710-06-6Relevant academic research and scientific papers
Construction of 1,3-Dithio-Substituted Tetralins by [1,5]-Alkylthio Group Transfer Mediated Skeletal Rearrangement
Hisano, Naoya,Kamei, Yuto,Kansaku, Yaoki,Yamanaka, Masahiro,Mori, Keiji
, p. 4223 - 4226 (2018/07/29)
A novel skeletal rearrangement involving a [1,5]-alkylthio group transfer/cyclization sequence is described. Treatment of benzylidene malonates having a thioketal moiety at the homobenzyl position with a catalytic amount of Sc(OTf)3 afforded alkylthio group rearranged adducts in good chemical yields. Detailed investigation of the reaction mechanism revealed that an intramolecular conjugate addition/ring opening sequence (not through-space transfer) is the key to achieving this reaction.
Synthesis of benzo[b]furans via CuI-catalyzed ring closure
Chen, Cheng-Yi,Dormer, Peter G.
, p. 6964 - 6967 (2007/10/03)
A wide variety of benzo[6]furans were synthesized efficiently via a CuI-catalyzed ring closure of 2-haloaromatic ketones. The methodology was tolerant to various functional groups, affording benzofurans in 72-99% yields.
The amine exchange/biaryl coupling sequence: A direct entry to the phenanthro[9,10-d]heterocyclic framework
Olivera, Roberto,SanMartin, Raul,Tellitu, Imanol,Domínguez, Esther
, p. 3021 - 3037 (2007/10/03)
Novel phenanthro[9,10-d]pyrimidines and phenanthro[9,10-d][1,2]oxazoles are regioselectively prepared by the application of a straightforward synthetic pathway, starting from new o,o′-dihalogenated and non-halogenated 4,5-diarylpyrimidines and 4,5-diaryli
