470716-41-7Relevant academic research and scientific papers
Aryl sulfones: A new class of γ-secretase inhibitors
Teall, Martin,Oakley, Paul,Harrison, Timothy,Shaw, Duncan,Kay, Euan,Elliott, Jason,Gerhard, Ute,Castro, Jose L.,Shearman, Mark,Ball, Richard G.,Tsou, Nancy N.
, p. 2685 - 2688 (2007/10/03)
The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived γ-secretase inhibitors for the potential treatment of Alzheimer's disease is described.
BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS
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Page 165; 166, (2010/02/08)
Provided are novel compounds having an inhibitory activity against production or secretion of β-amyloid protein. They embrace compounds represented by the following formula (1): and capable of being replaced with a variety of substituents; and salts thereof, and solvates of any one of them.
