470716-52-0

Basic information

• Product Name: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane
• Synonyms: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane;2-[[(4-chlorophenyl)thio]Methyl]-1,4-difluorobenzene
• CAS NO: 470716-52-0
• Molecular Formula: C₁₃H₉ClF₂S
• Molecular Weight: 270.7253664
• Mol File: 470716-52-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane(470716-52-0)
• EPA Substance Registry System: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane(470716-52-0)

Safety Data

• Hazardous Substances Data: 470716-52-0(Hazardous Substances Data)

Usage

Description

(4-chlorophenyl)(2,5-difluorobenzyl)sulfane is a sulfane compound characterized by a 4-chlorophenyl group connected to a (2,5-difluorobenzyl) group. As a sulfur analog of organic peroxides, this compound holds potential for various biological and pharmaceutical applications. Its distinctive structure and possible reactivity contribute to its significance in the realms of chemistry and pharmacology, making it a promising candidate for further research and development.

Uses

Used in Pharmaceutical Development:
(4-chlorophenyl)(2,5-difluorobenzyl)sulfane is utilized as a pharmaceutical candidate due to its potential biological activities. Its unique structure allows it to be explored for possible therapeutic applications, including the treatment of various diseases and conditions.
Used as a Chemical Intermediate in Organic Synthesis:
In the field of organic synthesis, (4-chlorophenyl)(2,5-difluorobenzyl)sulfane serves as a valuable chemical intermediate. Its reactivity and structural features make it suitable for use in the synthesis of more complex organic compounds, contributing to the advancement of chemical research and the development of new materials.
Used in Research and Development:
(4-chlorophenyl)(2,5-difluorobenzyl)sulfane is employed as a subject of interest in research and development within the fields of chemistry and pharmacology. Its potential applications and unique properties make it a valuable tool for scientists and researchers working to uncover new knowledge and create innovative solutions.

Upstream product

• 85117-99-3 2-(bromomethyl)-1,4-difluorobenzene 
• 106-54-7 p-Chlorothiophenol 
• 75853-20-2 2,5-difluoro-benzyl alcohol 

Downstream Products

• 471904-46-8 C₁₉H₁₈ClF₂NO₃S 
• 471905-38-1 C₂₂H₂₃ClF₂N₂O₄S 
• 471905-47-2 C₂₃H₂₅ClF₂O₄S 
• 471903-70-5 C₂₄H₂₆ClF₂NO₄S 
• 471903-19-2 5-(4-chloro-benzenesulfonyl)-5-(2,5-difluoro-phenyl)-2-hydroxy-cyclohex-1-enecarboxylic acid methyl ester 
• 471903-67-0 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid ethyl ester 
• 471903-66-9 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexylidene]-acetic acid ethyl ester 
• 471903-69-2 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid 
• 471903-41-0 trans-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 471905-53-0 cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 470716-51-9 2-[[(4-chlorophenyl)sulfonyl]methyl]-1,4-difluorobenzene 
• 558464-29-2 4-[[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl)methyl]tetrahydrothiopyrane 
• 558464-31-6 (RS)-tert-butyl 4-[(4-chlororbenzenesulfonyl)-(2,5-difluorophenyl)methyl]-piperidine-1-carboxylate 
• 852312-96-0 5-(4-chloro-benzenesulfonyl)-5-(2,5-difluoro-phenyl)-2-oxo-cyclohexanecarboxylic acid methyl ester 

Relevant articles and documents

A practical synthesis of a γ-secretase inhibitor

(Chemical Equation Presented) A practical and scaleable synthesis of the γ-secretase inhibitor 1 is reported. The inhibitor consists of a central trisubstituted cyclohexane core with appended propionic acid, 2,5-difluorophenyl, and 4-chlorophenylsulfonyl

CYCLOHEXYL SULPHONES FOR TREATMENT OF CANCER

Sulphones of formula (I) are disclosed for use in treatment of cancer.

The new cyclohexylpropionic sulfone

Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.