471282-15-2

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 471282-13-0 (2S,3S,4R)-2-benzenesulfonylmethyl-3,4-isopropylidenedioxy-tetrahydrofuran 
• 67-64-1 acetone 
• 219926-67-7 (2E,4E)-5-Phenylsulfonylpenta-2,4-dien-1-ol 
• 351439-90-2 (2S,3S,4E)-5-benzenesulfonyl-2,3-epoxy-pent-4-en-1-ol 
• 471282-03-8 (2S,3S,4E)-5-benzenesulfonyl-2,3-epoxy-pent-4-en-1-yl acetate 
• 471282-04-9 (2R,3S,4E)-5-benzenesulfonyl-1,2-isopropylidenedioxy-pent-4-en-3-ol 
• 471282-06-1 (2R,3S,4E)-5-benzenesulfonyl-2,3-isopropylidenedioxy-pent-4-en-1-yl acetate 

Relevant academic research and scientific papers

Synthesis of vinylsulfone derivatives of sugars: An easy preparation of (2R,3S,4E)-5-benzenesulfonyl-2,3-iso-propylidene-dioxy-pent-4-en-1-yl- tosylate

A two-step procedure for the synthesis of (2R,3S,4E)-5-benzenesulfonyl-2,3-isopropylidene-dioxypent-4-en-1-yl-tosylate is described. The method involves the addition of lithio(phenylsulfonyl)methane to 2,3-O-iso-propylidene-D-erythronolactol and treatment of the resulting diols with tosyl chloride.

Regio- and stereoselective ring opening of epoxides. Enantioselective synthesis of 2,3,4-trisubstituted five-membered heterocycles

By using the appropriate protecting groups, the opening of (2S,3S,4E)-5-benzenesulfonyl-2,3-epoxy-pent-4-en-1-ol (-)-2 could be controlled and used for the synthesis of the enantiomeric pyrrolidines (+)- and (-)-18 and the tetrahydrofuran analogs (+)- and (-)-19.