47145-36-8

Upstream product

• 120142-61-2 (-)-(1R,αS)-1,2,3,4-tetrahydro-6,7-dimethoxy-α-phenyl-1-isoquinolinemethanol 
• 120034-55-1 (1S)-1,2,3,4-tetrahydro-1-benzoyl-6,7-dimethoxy-2-<((R)-1-phenylethyl)carbamoyl>isoquinoline 
• 392662-77-0 (R)-1-Benzyl-6,7-dimethoxy-2-((R)-toluene-4-sulfinyl)-1,2,3,4-tetrahydro-isoquinoline 
• 122-78-1 phenylacetaldehyde 
• 22190-45-0 (6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)(phenyl)methanone 
• 120034-51-7 (+/-)-erythro-1,2,3,4-tetrahydro-6,7-dimethoxy-α-phenyl-1-isoquinolinemethanol 
• 120034-53-9 (1R,αS)-1,2,3,4-tetrahydro-6,7-dimethoxy-α-phenyl-2-<((R)-1-phenylethyl)carbamoyl>-1-isoquinolinemethanol 
• 392662-71-4 (R)-N-p-tolylsulfinyl 2-(3,4-dimethoxy)phenylethylamine 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 3423-37-8 1-benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Enantiopure tetrahydroisoquinolines via N-sulfinyl Pictet-Spengler reactions

Asymmetric Pictet-Spengler reactions with (R)-N-p-tolylsulfinyl-3,4-dimethoxyphenylethyl amine proceeded with high diastereoselectivity. Starting from the commercially available (R)- and (S)-Andersen reagents a highly efficient route to (+)- and (-)-salsolidine and related tetrahydroisoquinolines was developed.