4727-17-7Relevant articles and documents
Synthesis of α-Cyclooctyl- and α-Cyclopentadecylglycosides of N-Acetylmuramyl-L-Alanyl-D-Isoglutamine
Zemlyakov,Tsikalov,Tsikalova
, p. 1139 - 1142 (2018)
N-Acetylmuramyl-L-alanyl-D-isoglutamine α-cyclooctyl- and α-cyclopentadecylglycosides were synthesized. The starting peracetylated α-N-glucosaminides were synthesized by reacting the cycloalkanols with peracetyl α-D-glucosaminyl chloride in the presence of Hg(II) iodide in CH3NO2 with heating or by using ZnCl2/tetrabutylammonium bromide in CH2Cl2 at room temperature. Sequential deacetylation, isopropyl protection, and alkylation by (S)-2-bromopropanoic acid gave α-cycloalkyl-4,6-O-isopropylidene-N-acetyl-D-muramic acids, condensation of which with the benzyl ester of L-Ala-D-iGln using the HOSu/DCC method and deprotection afforded the target glycopeptides.
Pincerlike molybdenum complex and preparation method thereof, catalytic composition and application thereof, and alcohol preparation method
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Paragraph 0134-0140, (2021/08/11)
The invention discloses a clamp-type molybdenum complex, a preparation method, a corresponding catalyst composition and application. The method comprises the steps: obtaining 9 molybdenum complexes with different structures through coordination reaction of 2-(substituent ethyl)-(5, 6, 7, 8-tetrahydroquinolyl) amine and a corresponding carbonyl molybdenum metal precursor; and catalyzing a ketone compound transfer hydrogenation reaction through a molybdenum complex to generate 40 alcohol compounds. The preparation method of the molybdenum complex is simple, high in yield and good in stability. For a transfer hydrogenation reaction of ketone, the molybdenum-based catalytic system has high catalytic activity and small molybdenum loading capacity, is used for production of aromatic and aliphatic alcohols, and has the advantages of simple method, small environmental pollution and high yield.
Synthesis of β-cycloalkylglycosides of Muramyl Dipeptide
Zemlyakov,Tsikalova,Tsikalov
, p. 929 - 932 (2017/10/07)
β-Cyclooctyl-, β-cyclodecyl-, and β-cyclopentadecylglycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine were prepared in yields of 39, 18, and 25%, respectively, (calculated for muramic acid) via the reaction of β-cycloalkyl-4,6-O-isopropylidene-N-acetyl-D-muramic acids with the benzyl ester of L-Ala-D-iGln using the HOSu/DCC method followed by deprotection.