47292-84-2Relevant academic research and scientific papers
Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines
Yearick, Kimberly,Ekoue-Kovi, Kekeli,Iwaniuk, Daniel P.,Natarajan, Jayakumar K.,Alumasa, John,De Dios, Angel C.,Roepe, Paul D.,Wolf, Christian
, p. 1995 - 1998 (2008)
Systematic variation of the branching and basicity of the side chain of chloroquine yielded a series of new 7-chloro-4-aminoquinoline derivatives exhibiting high in vitro activity against four different strains of P. falciparum. Many of the compounds test
ANTIMALARIAL QUINOLINES AND METHODS OF USE THEREOF
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, (2009/12/28)
One aspect of the invention relates to substitute quinolines with antimalarial activity, and compositions and kits comprising at least one of them. Another aspect of the invention relates to methods for the treatment or prevention or both of malaria compr
