4732-10-9

Usage

Chemical structure

1-(phenylmethyl)refers to a chemical compound containing a phenylmethyl group, which is a benzyl group substituent.

Benzene ring

The phenylmethyl group is linked to a benzene ring, which is a six-membered ring with alternating single and double carbon-carbon bonds.

Methylene group

The phenylmethyl group also contains a methylene (CH2) group, which is a single carbon atom bonded to two hydrogen atoms.

Distinct structure

The combination of the benzene ring and methylene group creates a unique structure with potential biological and chemical properties.

Applications

Compounds with the 1-(phenylmethyl)group may have various applications, such as in pharmaceuticals, agrochemicals, and materials science.

Reactivity

The presence of the phenylmethyl group can influence the compound's reactivity, making it an important structural motif in organic chemistry.

Stability

The phenylmethyl group can also affect the stability of the compound, potentially enhancing or reducing its resistance to degradation.

Molecular interactions

The phenylmethyl group can impact the compound's interactions with other molecules, which may be relevant for its biological activity or chemical reactivity.

Upstream product

• 2835-21-4 allyl isocyanide 
• 100-39-0 benzyl bromide 
• 756462-76-7 (R)-1-benzyl-prop-2-enylamine 
• 244092-76-0 (R)-N-(tert-butoxycarbonyl)-3-amino-4-phenyl-1-butene 
• 140-29-4 phenylacetonitrile 
• 95092-10-7 N-methoxy-N-methyl-2-phenylacetamide 
• 37442-55-0 1-phenylbut-3-en-2-one 

Downstream Products

• 103127-52-2 ((S)-1-benzylallyl)carbamic acid tert-butyl ester 
• 126410-30-8 (S)-1-phenylbut-3-en-2-amine 
• 756462-76-7 (R)-1-benzyl-prop-2-enylamine 
• 220035-13-2 (S)-3-acetylamino-4-phenyl-1-butene 
• 220871-52-3 1(R,S)-<1'-(S)-<(tert-butyloxycarbonyl)amino>-2-phenylethyl>oxirane 
• 98760-08-8 (2R,3S)-3-[N-(tert-butyloxycarbonyl)amino]-1,2-epoxy-4-phenylbutane 
• 98760-08-8 (1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester 
• 149268-14-4 2(S)-methylsulfonylamino-1-phenyl-3-butene 
• 103127-52-2 4-phenyl-3-tert-butoxycarbonylamino-1-butene 

Relevant academic research and scientific papers

A method of preparing intermediates of luck sha neiwei

The invention provides a preparation method for a fosamprenir intermediate. The preparation method comprises the following steps: taking benzyl cyanide as a raw material, and performing steps of nitrile hydrolysis, acylation, reaction with a Grignard reagent, ammonization, cyclizing and the like for synthesizing (2R,3S)-1,2-epoxy-3-t-butyloxycarborylamino-4-phenyl butane. The method is reasonable in process, simple to operate, low in cost and high in yield; with the method, industrialization can be well realized and the production efficiency is improved.

Convenient method for synthesis of N-protected α-amino epoxides: Key intermediates for HIV protease inhibitors

A convenient method for synthesis of 2R,3S and 2S,3S N-Boc phenylalanine epoxides using readily available allylamine is described. Previous methods employed multistep synthetic routes from l-phenyl alanine that include use of m-chloroperbenzoic acid (m-CPBA) and a chromatographic method for purification of the desired diastereomers. Column purification could be eliminated by bringing in much improvement in the existing process. The process was further enhanced by replacing m-CPBA with oxone, an ecofriendly reagent advantageous for commercial application. The overall green process discussed involves the recovery and recycling of enantiomers of chiral allyl amines and judicial separation of diastereomers of the epoxides using simple economical methods.

Antiretroviral hydrazine derivatives

The invention relates to compounds of formula STR1 and salts, pharmaceutical compositions, intermediates and processes of preparation thereof.

Use of compositions for combating tumour diseases

The present invention relates to the use of inhibitors of HIV aspartate proteases, such as HIV-1- or HIV-2-protease, and their salts and to prodrugs for inhibiting the growth of tumors, especially those tumors which do not respond to the inhibition of HIV