473543-37-2

Upstream product

• 77-76-9 2,2-dimethoxy-propane 
• 163748-92-3 Acetic acid (2S,3R)-2,3-dihydroxy-3-phenyl-propyl ester 
• 622785-65-3 (4R-cis)-5-(2'-formylphenyl)-2,2-dimethyl-1,3-dioxolane-4-carboxaldehyde 
• 160707-67-5 (4S-cis)-5-[2'-(hydroxymethyl)phenyl]-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 473543-35-0 (4S-cis)-5-[2'-(formyl)phenyl]-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 473543-36-1 (4S-cis)-5-[2'-(formyl)phenyl]-2,2-dimethyl-1,3-dioxolane-4-methanol acetate 

Downstream Products

• 144429-71-0 (6R,7R,8R)-goniodiol-8-monoacetate 
• 473543-41-8 (1R)-1-[(4S,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]but-3-enyl acrylate 
• 473543-42-9 (6S)-6-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]-5,6-dihydro-2H-pyran-2-one 
• 473543-38-3 (1S)-1-((4S,5R)-2,2-dimethyl-5-phenyl-[1,3]-dioxolan-4-yl)-3-buten-1-ol 
• 473543-39-4 (1R)-1-((4S,5R)-2,2-dimethyl-5-phenyl-[1,3]-dioxolan-4-yl)-3-buten-1-ol 
• 474097-60-4 (6S)-6-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one 
• 163630-06-6 (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-5,6-dihydropyran-2-one 
• 146236-73-9 (+)-goniodiol 
• 130718-77-3 (4R,5R)-cis-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-carbaldehyde 
• 162600-00-2 ((4S,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl)methanol 

Relevant academic research and scientific papers

A total synthesis of the styryllactone (+)-goniodiol from naphthalene

The cytotoxic natural product (+)-goniodiol (1) has been prepared in twelve steps from the enantiomerically pure cis-dihydrocatechol (2), which is readily obtained by microbial oxidation of naphthalene. Elaboration of compound (2) involves an initial oxid

A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene

The enantiomerically pure cis-1,2-diol 2, which is obtained by microbial oxidation of naphthalene, has been converted, via a sequence of reactions including oxidative C-C bond cleavage, decarbonylation and ring-closing metathesis steps, into the natural p

Total synthesis of the natural goniodiol-8-monoacetate from cinnamyl alcohol

The first total synthesis of goniodiol-8-monoacetate, using the Sharpless asymmetric epoxidation starting from cinnamyl alcohol in twelve steps with an overall yield of 7%, is achieved.