473552-22-6

Upstream product

• 831196-83-9 p-benzyloxy-ω-azidoacetophenone 
• 473552-31-7 (R)-1-(4-benzyloxyphenyl)-2-(p-tolylsulfonyloxy)ethanol 

Downstream Products

• 831196-82-8 N-[2-(4-benzyloxy-phenyl)-2-hydroxy-ethyl]-2-(3,4-dimethoxy-phenyl)-acetamide 
• 71771-90-9 denopamine 
• 63365-60-6 (R)-1-(p-benzyloxyphenyl)-2-[2-(3,4-dimethoxyphenyl)ethylamino]ethanol 
• 473552-26-0 (R)-(-)-2-amino-1-(p-benzyloxyphenyl)ethanol 
• 876-04-0 (R)-octopamine 

Relevant academic research and scientific papers

Chemoenzymatic synthesis of (R)- and (S)-tembamide, aegeline and denopamine by a one-pot lipase resolution protocol

An efficient synthesis of optically active β-azido alcohols from their ketoazides by a one-pot reduction and an in situ lipase resolution protocol is described. The synthetic utility of this procedure has been illustrated by its application in the practic

Asymmetric transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives: synthesis of (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine

Catalytic transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives leads to efficient synthesis of β-adrenergic agonists, (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine.

Application of optically active 1,2-diol monotosylates for synthesis of β-azido and β-amino alcohols with very high enantiomeric purity. Synthesis of enantiopure (R)-octopamine, (R)-tembamide and (R)-aegeline

A very convenient and highly efficient synthesis of near enantiopure β-azido and β-amino alcohols including biologically active substances such as (R)-octopamine, (R)-tembamide and (R)-aegeline from optically active 1,2-diol monotosylates is reported.