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71771-90-9

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71771-90-9 Usage

Description

Denopamine is a potent orally-active cardiotonic with selective effects on the beta, adrenergic receptors. Unlike isoproterenol or dobutamine, denopamine’s positive inotropic activity is not mediated through the release of catecholamines; its lack of effect on heart rate and myocardial oxygen consumption thus offers significant advantages in the management of congestive heart failure.

Uses

R(-)-Denopamine has been used as an β-adrenergic agonist to study its effects on contractility in isolated lymphatic vessels (LVs).

Brand name

Kalgut

Biochem/physiol Actions

Denopamine is a cardiotonic drug.

Check Digit Verification of cas no

The CAS Registry Mumber 71771-90-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,7,7 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 71771-90:
(7*7)+(6*1)+(5*7)+(4*7)+(3*1)+(2*9)+(1*0)=139
139 % 10 = 9
So 71771-90-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H23NO4/c1-22-17-8-3-13(11-18(17)23-2)9-10-19-12-16(21)14-4-6-15(20)7-5-14/h3-8,11,16,19-21H,9-10,12H2,1-2H3/t16-/m0/s1

71771-90-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name R(-)-DENOPAMINE

1.2 Other means of identification

Product number -
Other names (R)-4-{2-[2-(3,4-dimethoxy-phenyl)-ethylamino]-1-hydroxy-ethyl}-phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71771-90-9 SDS

71771-90-9Relevant articles and documents

Denopamine and preparation method of intermediate of denopamine

-

Paragraph 0050-0058, (2020/01/03)

The invention discloses denopamine and a preparation method of an intermediate of denopamine, and particularly provides a method for preparing denopamine by Ir/f-amphox catalytic asymmetric hydrogenation. According to the method, steps are simple, operati

Asymmetric transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives: synthesis of (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine

Lee, Do-Min,Lee, Jong-Cheol,Jeong, Nakcheol,Lee, Kee-In

, p. 2662 - 2667 (2008/09/16)

Catalytic transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives leads to efficient synthesis of β-adrenergic agonists, (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine.

A convenient stereoselective synthesis of (R)-(-)-denopamine and (R)-(-)-salmeterol

Goswami, Jonali,Bezbaruah, Rajiv L.,Goswami, Amrit,Borthakur, Naleen

, p. 3343 - 3348 (2007/10/03)

β-Adrenoreceptor agonists (R)-(-)-denopamine (R)-1 and (R)-(-)-salmeterol (R)-2 have been prepared in good overall yield and high enantioselectivity through a biotransformative pathway.

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