473739-41-2Relevant academic research and scientific papers
Synthesis of thiohydantoins by phosphine-catalyzed reaction of thioureas with arylpropiolates
Carboni, Michael,Gomis, Jean-Marie,Loreau, Olivier,Taran, Frederic
, p. 417 - 424 (2008/09/20)
A simple and efficient method for constructing thiohydantoin heterocycles using a phosphine-catalyzed tandem umpolung addition and intramolecular cyclization of thioureas on arylpropiolates is described. Georg Thieme Verlag Stuttgart.
Synthesis of 3-substituted 5-arylidene-1-methyl-2-Thiohydantoins under microwave irradiation
Khodair, Ahmed I.,Nielsen, John
, p. 1017 - 1032 (2007/10/03)
A mono-modal microwave oven was used to expedite the synthesis of small libraries of 3-substituted 1-methyl-2-thiohydantoins and 3-substituted 5-arylidene-1-methyl-2-thiohydantoins. In comparison with the traditional reflux methods, similar or higher yields were obtained.
