473758-90-6Relevant articles and documents
Towards a total synthesis of (-)-cephalotaxine: Construction of the BCDE-tetracyclic core
Worden, Stephen M,Mapitse, Renameditswe,Hayes, Christopher J
, p. 6011 - 6014 (2002)
The synthesis of the BCDE-tetracyclic core of (-)-cephalotaxine has been achieved in eight steps starting from N-Boc-L-proline methyl ester. An alkylidene carbene 1,5-CH insertion reaction was used as a key step in the stereocontrolled synthesis of the DE