473933-46-9

Upstream product

• 1009-61-6 1,4-Diacetylbenzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 201230-82-2 carbon monoxide 
• 99-90-1 para-bromoacetophenone 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 473933-48-1 (E)-3-(4-Methoxy-phenyl)-1-{4-[(E)-(3-phenyl-acryloyl)]-phenyl}-propenone 
• 473933-50-5 2,3-dibromo-1-[4-(2,3-dibromo-3-phenyl-propionyl)-phenyl]-3-(4-methoxy-phenyl)-propan-1-one 

Relevant academic research and scientific papers

Palladium-catalyzed carbonylative addition of aryl bromides to arylalkynes: A simple and efficient method for chalcone synthesis

Palladium-catalyzed carbonylative addition of aryl bromides to terminal arylalkynes was carried out to produce chalcones in satisfactory to excellent yields. The unprecedented carbonylation reaction proceeded smoothly under mild conditions in the presence

Synthesis of new molecules containing head, spacer, and label moieties

We describe the synthesis and characterization of novel molecules containing head with precise shape, spacer, and label moieties. The protocol is based on a Pd(0)-catalyzed cross-coupling reaction between ethynylphenyl/bromide to obtain a rigid head followed by the attachment of a flexible spacer possessing two reactive functional groups on the termini. The final step consists of forming a covalent bond between spacer and label. In addition, monosubstituted soluble labels were synthesized in good yields.