473987-31-4

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 621-84-1 O-benzyl carbamate 
• 787552-03-8 3-(tert-butyl-dimethyl-silanyloxy)-1-(4,4-dimethoxy-cyclohex-1-enyl)-propan-1-ol 
• 24165-60-4 1-(4-methoxyphenyl)but-3-en-1-ol 
• 70760-15-5 1-(4'-Methoxyphenyl)-1,3-propanediol 
• 123-11-5 4-methoxy-benzaldehyde 
• 473987-30-3 1-(4,4-dimethoxy-cyclohex-1-enyl)-propane-1,3-diol 

Relevant academic research and scientific papers

Synthetic approach to tetrodotoxin

A novel and stereoselective approach to tetrodotoxin is described. The tricyclic compound having several key functional groups on the cyclohexane ring was synthesized from p-anisaldehyde with control of the four chiral centers. Iodoaminocyclization, 1,3-dipolar cycloaddition, and Baeyer-Villiger oxidation are the key steps of our approach.