474-53-3Relevant academic research and scientific papers
An unexpected reaction of cinobufagin analogues in the presence of PPh3/I2
Chen, Xubing,Guo, Dean,Hou, Jinjun,Lei, Min,Long, Huali,Wu, Wanying,Zhang, Yanzhi,Zhang, Zijia,Zhou, Yang
, (2020/05/04)
Abstract: An unexpected reaction of cinobufagin analogues in the presence of PPh3/I2 in EtOAc at room temperature to obtain diene compounds has been described. The whole process is carried out under mild conditions and the desired products are formed in good yields. It provides a simple, effective, and novel reaction method for the synthesis of diene compounds from corresponding substrates. Graphic abstract: [Figure not available: see fulltext.]
