474055-66-8

Usage

Uses

Used in Health and Wellness Applications:
((E)-3-isothiocyanatoprop-1-enyl)benzene is used as a natural compound with potential health benefits due to its antioxidant, anti-inflammatory, and antimicrobial properties. It may contribute to the prevention and treatment of various diseases and conditions.
Used in Cancer Prevention and Treatment:
((E)-3-isothiocyanatoprop-1-enyl)benzene is used as a potential anti-cancer agent for its ability to inhibit the growth of certain cancer cells. Further research is needed to explore its full potential in this area.
Used in Cardiovascular Disease Prevention and Treatment:
((E)-3-isothiocyanatoprop-1-enyl)benzene is used as a potential agent for preventing and treating cardiovascular diseases, given its potential health benefits.
Used in Diabetes Prevention and Treatment:
((E)-3-isothiocyanatoprop-1-enyl)benzene is used as a potential agent for preventing and treating diabetes, based on its potential health benefits.
Used in Food Industry:
((E)-3-isothiocyanatoprop-1-enyl)benzene is used as a flavoring agent in the food industry, particularly for its pungent aroma and taste found in plants like horseradish and mustard.

Upstream product

• 75-15-0 carbon disulfide 
• 52966-67-3 N-cinnamyl-trifluoroacetamide 
• 2290-65-5 trimethylsilyl isothiocyanate 
• 40595-34-4 (E)-trimethyl(3-phenylallyl)silane 
• 4392-24-9 Cinnamyl bromide 
• 43219-51-8 (E)-(3-isocyanoprop-1-en-1-yl)benzene 
• 57294-86-7 (E)-cinnamyl azide 
• 74394-96-0 (E)-(3-thiocyanatoprop-1-en-1-yl)benzene 

Downstream Products

• 7472-35-7 N-cinnamylbenzothioamide 
• 65984-69-2 N-phenyl-N'-trans-cinnamyl-thiourea 

Relevant academic research and scientific papers

Efficient synthesis of isothiocyanates based on the tandem Staudinger/aza-Wittig reactions and mechanistic consideration of the tandem reactions

The tandem and stepwise Staudinger/aza-Wittig reactions of several azides were examined in detail. The tandem reaction method (Method I) exhibited superior results in the yield of the corresponding isothiocyanates bearing an electron-withdrawing group than the conventional stepwise method (Method II) which involves the sequential treatment of the azides with triphenylphosphine and then carbondisulfide. The mechanistic consideration for both reaction methods was proposed on the basis of the 1H-NMR analyses.

Direct synthesis of isothiocyanates from isonitriles by molybdenum-catalyzed sulfur transfer with elemental sulfur

The direct molybdenum-catalyzed sulfuration of a variety of isonitriles with elemental sulfur or propene sulfide as sulfur donors affords the corresponding isothiocyanates in good yields and under mild reaction conditions. A catalytic cycle is suggested, in which the molybdenum oxo disulfur complex operates as the active sulfur-transferring species. A novel adduct between the isonitrile and the molybdenum complex has been characterized by X-ray analysis and its association constant determined by UV-vis spectroscopy, but this adduct appears not to be involved in the sulfur-transfer process.

Ambidient Cationic Behavior of +>: Reactions of Vinyl and Allyl Metals with TMSNCS/ Halogen-Oxidants Agent

The first and clear ambidient character og the SCN cation during the reaction with vinylic and allylic metals are described.

Synthesis of isothiocyanates by reaction of amides with carbon disulfide in the presence of solid potassium carbonate/sodium hydroxide mixture

Readily available N-monosubstituted trifluoroacetamides are transformed into isothiocyanates in good yield by reaction, at room temperature, with carbon disulfide in acetonitrile in the presence of anhydrous sodium hydroxide/potassium carbonate basic mixture.