474302-77-7

Upstream product

• 355839-65-5 (-)-3-{[(2R,5S)-2,5-dihydro-5-(1-methylethyl)pyrazinyl]methyl}-6-methoxy-2-(triethylsilyl)-1H-indole 
• 355839-49-5 (2S,5R)-3,6-diethoxy-2-isopropyl-5-[3-(triethylsilyl)prop-2-ynyl]-2,5-dihydropyrazine 
• 153898-63-6 2-iodo-5-methoxyaniline 
• 100-52-7 benzaldehyde 
• 474302-74-4 trans-(1S,3R)-(-)-2-benzyl-3-ethoxycarbonyl-7-methoxy-1-methoxycarbonylethyl-9-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole 
• 853072-54-5 C₂₅H₂₆N₂O₄ 

Relevant academic research and scientific papers

Regiospecific, enantiospecific total synthesis of the alkoxy-substituted indole bases, 16-epi-Na-methylgardneral, 11-methoxyaffinisine, and 11-methoxymacroline as well as the indole alkaloids alstophylline and macralstonine

(matrix presented) A regiospecific, enantiospecific approach to the synthesis of ring-A-substituted indole alkaloids was developed via a doubly convergent strategy. The asymmetric Pictet-Spengler reaction and enolate-driven palladium cross-coupling proces

A general strategy for the synthesis of vincamajine-related indole alkaloids: Stereocontrolled total synthesis of (+)-dehydrovoachalotine, (-)-vincamajinine, and (-)-11-methoxy-17-epivincamajine as well as the related quebrachidine diol, vincamajine diol,

The highly convergent stereocontrolled total synthesis of (-)-vincamajinine (7), (-)-11-methoxy-17-epivincamajine (9), and the oxygen-bridged (+)-dehydrovoachalotine (22) are described. Key steps in the synthesis of 7 and 9 involved the stereospecific eno