4746-93-4

Usage

Uses

Used in Pharmaceutical Synthesis:
1,4-dioxaspiro[4.5]decane-6-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structural properties and reactivity.
Used in Organic Synthesis:
1,4-dioxaspiro[4.5]decane-6-carboxylic acid serves as a building block in organic synthesis, contributing to the creation of diverse organic compounds due to its complex molecular structure and functional group.

Upstream product

• 107-21-1 ethylene glycol 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 60-29-7 diethyl ether 
• 16493-10-0 2-butyrylcyclohexanone 
• 13747-72-3 ethyl 1,4-dioxa-spiro[4,5]decane-6-carboxylate 

Downstream Products

• 78632-11-8 N-<2-(3,4-Dimethoxyphenyl)ethyl>-2,2-ethylendioxy-1-cyclohexancarboxamid 
• 165590-67-0 1-<(1,4-dioxaspiro<4.5>decan-6-yl)carbonyl>-1,2,3,6-tetrahydro-4-phenylpyridine 
• 854133-07-6 1,4-dioxa-spiro[4.5]decane-6-carbonyl chloride 
• 1028312-90-4 1-(1,4-Dioxa-spiro[4.5]dec-6-ylmethyl)-4-phenyl-1,2,3,6-tetrahydro-pyridine 
• 1026575-85-8 1-Phenyl-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-cyclohexanol 
• 788133-17-5 2-<(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)methyl>cyclohexanone 
• 78632-05-0 (Z)-2-<2-Acetyl-3,4-dihydro-6,7-dimethoxy-1(2H)-isochinolinyliden>cyclohexanon 
• 78632-06-1 (E)-2-<2-Acetyl-3,4-dihydro-6,7-dimethoxy-1(2H)-isochinolinyliden>cyclohexanon 
• 78631-98-8 2-(3,4-Dihydro-6,7-dimethoxy-1-isochinolinyl)-1-cyclohexen-1-ol 
• 78632-13-0 N-<2-(3,4-Dimethoxyphenyl)ethyl>-2,3,6,7,8,9-hexahydro-5H-1,4-benzodioxepin-5-imin 
• 78632-09-4 2-(6,7-Dimethoxy-1-isochinolinyl)cyclohexanon 
• 78632-12-9 2-Oxo-cyclohexanecarboxylic acid [2-(3,4-dimethoxy-phenyl)-ethyl]-amide 
• 78632-08-3 2-(6,7-Dimethoxy-1-isochinolinyl)phenol 
• 144019-82-9 N-<(phenyloxy)carbonyl>-10-<(tert-butyldimethylsilyl)oxy>-6a,10a-epoxy-6-ethynyl-3-(trimethylacetoxy)-5,6,6a,7,8,9,10,10a-octahydrophenanthridine 

Relevant academic research and scientific papers

Process for the Preparation of Substituted 1-aminomethyl-2-phenyl-cyclohexane Compounds

A process for the preparation of substituted 1-aminomethyl-2-phenyl-cyclohexane compounds.

PROCESS FOR THE PREPARATION OF SUBSTITUTED 1-AMINOMETHYL-2-PHENYL-CYCLOHEXANE COMPOUNDS

The present invention relates to a process for the preparation of substituted 1-aminomethyl-2-phenyl-cyclohexane compounds.

CALCILYTIC COMPOUNDS

Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.

Multicomponent reactions involving tricyclooxonium ylide intermediate: Diastereoselective synthesis of mono- and bisalkoxyoctahydro-1,4-benzodioxocin- 6(5H)-one frameworks

A highly diastereoselective tandem ring-enlargement and aldol condensation process involving multicomponent reactions of ethereal tricyclooxonium ylide intermediate with alcohols, mono- or dialdehydes in the presence of titanium(iv) isopropoxide is descri

Design, new synthesis, and calcilytic activity of substituted 3H-pyrimidin-4-ones

Design, new synthesis, structure-activity relationship studies and calcium receptor antagonist (calcilytic) properties of novel 3H-pyrimidin-4-ones are described.

Dynemicin analogs: syntheses, methods of preparation and use

A fused ring system compound is disclosed that contains an epoxide group on one side of the fused rings and an enediyne macrocyclic ring on the other side of the fused rings. The compounds have DNA-cleaving, antimicrobial and tumor growth-inhibiting properties. Chimeric compounds having the fused ring system compound as an aglycone bonded to (i) a sugar moiety as the oligosaccharide portion or (ii) a monoclonal antibody or antibody combining site portion thereof that immunoreacts with target tumor cells are also disclosed. Compositions containing a compound or a chimer are disclosed, as are methods of preparing a compound.

Dynemicin analogs: synthesis, methods of preparation and use

A fused ring system compound is disclosed that contains an epoxide group on one side of the fused rings and an enediyne macrocyclic ring on the other side of the fused rings. The compounds have DNA-cleaving, antimicrobial and tumor growth-inhibiting properties. Chimeric compounds having the fused ring system compound as an aglycone bonded to (i) a sugar moiety as the oligosaccharide portion or (ii) a monoclonal antibody or antibody combining site portion thereof that immunoreacts with target tumor cells are also disclosed. Compositions containing a compound or a chimer are disclosed, as are methods of preparing a compound.

The Discovery and Structure-Activity Relationships of 1,2,3,6-Tetrahydro-4-phenyl-1-pyridines. Dopamine Autoreceptor Agonists and Potential Antipsychotic Agents

A novel dopamine (DA) autoreceptor agonist, 1,2,3,6-tetrahydro-4-phenyl-1-pyridine (14), was identified.The structure-activity relationships surrounding this compound were studied by synthesis of analogues and evaluatio

Molecular design and chemical synthesis of potent enediynes. 2. Dynemicin model systems equipped with C-3 triggering devices and evidence for quinone methide formation in the mechanism of action of dynemicin A

Continuing the theme of the preceding article, this paper describes the synthesis and chemical properties of designed enediynes related to dynemicin A. These model systems are equipped with triggering devices at C-3 of the aromatic nucleus. The design of

A Reversible Rearrangement of the trans-Erythrinane Ring System, IV. Ivestigations Concerning the Reaction Mechanism

The labelled β-lactame carboxylic acid 10a is prepared via the diol-A 7.The products of thermal decarboxylation 11a and 12a include the whole activity of the original carboxylic acid 10a.On the other hand, decarboxylation of 10a with sulfuric ac