474645-90-4

Basic information

• Product Name: (R)-3-[4-(trifluoromethyl)phenylamino]-pentanoic acid
• Synonyms: (R)-3-[4-(trifluoromethyl)phenylamino]-pentanoic acid
• CAS NO: 474645-90-4
• Molecular Weight: 261.244
• Mol File: 474645-90-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-3-[4-(trifluoromethyl)phenylamino]-pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-[4-(trifluoromethyl)phenylamino]-pentanoic acid(474645-90-4)
• EPA Substance Registry System: (R)-3-[4-(trifluoromethyl)phenylamino]-pentanoic acid(474645-90-4)

Safety Data

• Hazardous Substances Data: 474645-90-4(Hazardous Substances Data)

Upstream product

• 1027896-34-9 (R)-4-ethyl-1-[4-(trifluoromethyl)phenyl]-2-azetidinone 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 142342-74-3 (R)-3-amino-valeric acid ethyl ester 
• 80914-37-0 (R)-β-aminopentanoic acid hydrochloride 
• 131347-76-7 (R)-β-aminopentanoic acid 

Downstream Products

• 667937-05-5 (3R)-3-(4-trifluoromethylphenylamino)pentanoic acid amide 

Relevant articles and documents

A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES

The present invention is to provide a process for preparing optically active tetrahydroquinoline derivatives which can be used for the treatment and/or prevention of diseases such as arteriosclerotic diseases, dyslipidemia and the like, and a process for preparing synthetic intermediates thereof. Specifically, (2R,4S)-2-ethyl-6-trifluoromethyl-1,2,3,4-tetrahydroquinolin-4-ylamine or a salt thereof is prepared with fewer steps without using an optical resolution, and the optically active tetrahydroquinoline derivatives are obtained from the amine compound.