474668-60-5Relevant academic research and scientific papers
Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides
Chien, Chen-Yu,Yu, Sheng-Sheng
supporting information, p. 11949 - 11952 (2020/10/15)
The ester-amide exchange reaction enables spontaneous formation of prebiotic proto-peptides under mild conditions. However, this reaction also leads to oligomers with a vast sequence diversity of ester and amide linkages. Here, we demonstrate using deep eutectic solvents as a universal strategy to regulate the reaction pathways and promote the formation of amino acid-enriched oligomers with peptide backbones.
