475084-44-7

Upstream product

• 101563-68-2 6-oxo-3-phenyl-1,6-dihydropyridazine-4-carbaldehyde 
• 108-59-8 malonic acid dimethyl ester 
• 475084-42-5 1-methoxymethyl-6-oxo-3-phenyl-1,6-dihydropyridazine-4-carbaldehyde 
• 90766-97-5 5-bromo-6-phenylpyridazin-3(2H)-one 
• 247158-81-2 2-methoxymethyl-6-phenyl-5-vinyl-3(2H)-pyridazinone 
• 247158-79-8 5-Bromo-2-methoxymethyl-6-phenylpyridazin-3-one 

Downstream Products

• 1001620-53-6 C₁₄H₁₀N₂O₅ 

Relevant academic research and scientific papers

Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity

5-Alkylidenepyridazin-3-ones with four points of diversity (R2, R6, X, Y) have been synthesized and evaluated as platelet aggregation inhibitors. Several derivatives eliciting antiplatelet activity in the low micromolar range (e.g.,

Pyridazines. Part 28: 5-Alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors

The synthesis and anti-platelet activity of several 5-alkylidene-6-phenyl-3(2H)-pyridazinones are described. The most active compounds are those that contain oxygenated functions (COOR, COMe) on the alkylidene fragment (6a, 6b and 6c).