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1-Piperidinecarboxylic acid, 4-(4-chlorophenyl)-4-hydroxy-3,3-dimethyl-, 1,1-dimethylethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • tert-butyl 4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carboxylate

    Cas No: 475085-56-4

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  • 475085-56-4 Structure
  • Basic information

    1. Product Name: 1-Piperidinecarboxylic acid, 4-(4-chlorophenyl)-4-hydroxy-3,3-dimethyl-, 1,1-dimethylethyl ester
    2. Synonyms:
    3. CAS NO:475085-56-4
    4. Molecular Formula: C18H26ClNO3
    5. Molecular Weight: 339.862
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 475085-56-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-(4-chlorophenyl)-4-hydroxy-3,3-dimethyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-(4-chlorophenyl)-4-hydroxy-3,3-dimethyl-, 1,1-dimethylethyl ester(475085-56-4)
    11. EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-(4-chlorophenyl)-4-hydroxy-3,3-dimethyl-, 1,1-dimethylethyl ester(475085-56-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 475085-56-4(Hazardous Substances Data)

475085-56-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 475085-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,0,8 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 475085-56:
(8*4)+(7*7)+(6*5)+(5*0)+(4*8)+(3*5)+(2*5)+(1*6)=174
174 % 10 = 4
So 475085-56-4 is a valid CAS Registry Number.

475085-56-4Relevant articles and documents

CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF

-

, (2016/02/21)

Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.

The discovery of BMS-457, a potent and selective CCR1 antagonist

Gardner, Daniel S.,Santella III, Joseph B.,Duncia, John V.,Carter, Percy H.,Dhar, T.G.Murali,Wu, Hong,Guo, Weiwei,Cavallaro, Cullen,Van Kirk, Katy,Yarde, Melissa,Briceno, Stephanie W.,Robert Grafstrom,Liu, Richard,Patel, Sima R.,Tebben, Andrew J.,Camac, Dan,Khan, Javed,Watson, Andrew,Yang, Guchen,Rose, Anne,Foster, William R.,Cvijic, Mary Ellen,Davies, Paul,Hynes Jr., John

, p. 3833 - 3840 (2013/07/25)

A series of compounds which exhibited good human CCR1 binding and functional potency was modified resulting in the discovery of a novel series of high affinity, functionally potent antagonists of the CCR1 receptor. Issues of PXR activity, ion-channel pote

PRODRUGS OF A PIPERIDINYL DERIVATIVE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

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Page/Page column 22, (2011/04/24)

The present application describes prodrugs of the compound of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well a

NOVEL COMPOUNDS USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS

-

Page/Page column 32, (2010/07/08)

The present invention relates to novel morpholine, oxazapane and piperidine derivatives that act as ligands for CC chemokine receptors, such as CCR1. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

PIPERIDINYL DERIVATIVE AS A MODULATOR OF CHEMOKINE RECEPTOR ACTIVITY

-

Page/Page column 14, (2010/01/30)

The present application describes the compound of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune

Chemokine receptor antagonists and methods of use thereof

-

, (2008/06/13)

Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: formula (1) or physiologically acceptable salt thereof.

CCR1 antagonists and methods of use therefor

-

Page/Page column 8, (2010/02/07)

The invention provides compounds having the formula: wherein R1 is halogen. The invention also provides compositions comprising the compounds, and methods of treating diseases or disorders that comprise administering one or more of the compound

Chemokine receptor anagonists and methods of use therefor

-

, (2008/06/13)

Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.

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