475095-97-7Relevant academic research and scientific papers
Structure and base catalysed cyclization of methyl (2,6-disubstituted-4-nitrophenylsulphanyl)ethanoates
Bertolasia, Valerio,Dudová, Ka?ehna,?im?nek, Petr,?erny, Ji?í,Machá?ek, Vladimír
, p. 33 - 42 (2003)
The conformation of side chain - SCH2COOCH3 in title compounds in crystal agrees with the reactivity of these compounds in base catalysed ring closure in solution. In the 2,4-dinitro derivative, the side chain is oriented towards the
Preparation of substituted methyl o-nitrophenyl sulfides
Dudova, Katerina,Castek, Frantisek,Machacek, Vladimir,Simunek, Petr
, p. 7 - 17 (2007/10/03)
The nucleophilic substitution of substituted o-nitrochlorobenzenes with substituted methanethiolates, catalysed with triethylamine or pyridine, has been used to prepare a series of appropriately substituted methyl-o- nitrophenylsulfides. The prepared compounds were identified by their 1H- and 13C-NMR spectra. The base catalysed ring closure of methyl 2-(methoxycarbonylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate only results in an attack of carbanion on the ester group, not on a nitro group as with the other compounds prepared. The cyclisation product is methyl 3-hydroxy-5,7-dinitro-benzo[b]thiophene-2-carboxylate (11).
