475143-08-9

Upstream product

• 374896-36-3 ethyl (2R,3S,4S)-2-bromo-5-(tert-butyldimethylsiloxy)-3-hydroxy-2,4-dimethylpentanoate 
• 475051-45-7 (2R,3S,4S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-2,4-dimethyl-pentanoic acid ethyl ester 
• 184292-01-1 (2R,3S,4S)-5-(tert-butyldimethylsiloxy)-3-(4-methoxybenzyloxy)-2,4-dimethylpentanal 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 125244-91-9 3-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2-methylpropan-1-ol 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 104701-87-3 3-tert-butyldimethylsilyloxy-2-methylpropanal 
• 475143-06-7 ethyl (2R,3S,4R,5S,6S)-2-bromo-7-(tert-butyldimethylsiloxy)-3-hydroxy-5-(4-methoxybenzyloxy)-2,4,6-trimethylheptanoate 

Relevant academic research and scientific papers

A short synthesis of the C15-C21 segment of (+)-discodermolide, based on an asymmetric approach from achiral 2-methyl-1,3-propanediol to versatile enantiopure stereotriads

A new approach was developed to versatile enantiopure stereotriads using chiral oxazaborolidinone-promoted asymmetric aldol reaction of a racemic aldehyde with a bromo silyl nucleophile. A short synthesis of the C15-C21 segment of (+