475160-73-7

Basic information

• Product Name: (+/-)-1-[4-(tert-butyldiphenylsilanoxymethyl)phenyl]-4-(trimethylsilanyl)-but-3-yn-1-ol
• Synonyms: (+/-)-1-[4-(tert-butyldiphenylsilanoxymethyl)phenyl]-4-(trimethylsilanyl)-but-3-yn-1-ol
• CAS NO: 475160-73-7
• Molecular Weight: 486.802
• Mol File: 475160-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-1-[4-(tert-butyldiphenylsilanoxymethyl)phenyl]-4-(trimethylsilanyl)-but-3-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-1-[4-(tert-butyldiphenylsilanoxymethyl)phenyl]-4-(trimethylsilanyl)-but-3-yn-1-ol(475160-73-7)
• EPA Substance Registry System: (+/-)-1-[4-(tert-butyldiphenylsilanoxymethyl)phenyl]-4-(trimethylsilanyl)-but-3-yn-1-ol(475160-73-7)

Safety Data

• Hazardous Substances Data: 475160-73-7(Hazardous Substances Data)

Upstream product

• 38002-45-8 3-bromo-1-(trimethylsilyl)-1-propyne 
• 196880-47-4 4-({[tert-butyl(diphenyl)silyl]oxy}methyl)benzaldehyde 
• 146952-73-0 [4-({[tert-butyl(diphenyl)silyl]oxy}methyl)phenyl]methanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 589-29-7 p-xylylene glycol 

Downstream Products

• 475160-78-2 (1S)-1-[4-(tert-butyldiphenylsilanyloxymethyl)phenyl]-2-oxiranyl-ethanol 
• 475161-07-0 (1R)-1-[4-(tert-butyldiphenylsilanyloxymethyl)phenyl]-2-oxiranyl-ethanol 

Relevant articles and documents

Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin.

Seventy-two hundred potential inhibitors of the histone deacetylase (HDAC) enzyme family, based on a 1,3-dioxane diversity structure, were synthesized on polystyrene macrobeads. The compounds were arrayed for biological assays in a "one bead-one stock sol