475271-37-5Relevant academic research and scientific papers
An efficient synthesis of a dual PPAR α/γ agonist and the formation of a sterically congested α-aryloxyisobutyric acid via a Bargellini reaction
Cvetovich, Raymond J.,Chung, John Y. L.,Kress, Michael H.,Amato, Joseph S.,Matty, Louis,Weingarten, M. David,Tsay, Fuh-Rong,Li, Zhen,Zhou, George
, p. 8560 - 8563 (2005)
A practical synthesis of benzisoxazole 1 and its conversion to α-aryloxyisobutyric acid 2 using 1,1,1-trichloro-2-methyl-2-propanol (chloretone) was developed. Benzisoxazole 1 was formed in high yields by the action of either methanesulfonyl chloride/base
