(1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime

Base Information

• Chemical Name: (1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime
• CAS No.: 475271-37-5
• Molecular Formula: C₁₄H₁₈F₃NO₃
• Molecular Weight: 305.297
• Mol file: 475271-37-5.mol

Synonyms:(1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime

Chemical Property of (1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime

There total 2 articles about (1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone (355387-55-2) → (1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime (475271-37-5)

Guidance literature:

With hydroxylamine; N-butylamine; In methanol; water; at 60 ℃; for 17.5h;

DOI:10.1021/jo051027+

Reference yield:

2,4-di-n-propylbenzene-1,3-diol (355387-54-1) → (1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime (475271-37-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine; n-butylamine / methanol; H₂O / 17.5 h / 60 °C

With hydroxylamine; N-butylamine; In methanol; water;

DOI:10.1021/jo051027+

Reference yield:

(1E)-1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone oxime (475271-37-5) + methanesulfonyl chloride (124-63-0) → C15H20F3NO5S

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In Isopropyl acetate;

DOI:10.1021/jo051027+

upstream raw materials:

1-(2,4-dihydroxy-3,5-dipropylphenyl)-2,2,2-trifluoroethanone

2,4-di-n-propylbenzene-1,3-diol