475272-38-9Relevant academic research and scientific papers
Development of a potent Bcl-xL antagonist based on α-helix mimicry
Kutzki, Olaf,Park, Hyung Soon,Ernst, Justin T.,Orner, Brendan P.,Yin, Hang,Hamilton, Andrew D.
, p. 11838 - 11839 (2002)
The rational design of low-molecular weight ligands that disrupt protein-protein interactions is still a challenging goal in medicinal chemistry. Our approach to this problem involves the design of molecular scaffolds that mimic the surface functionality
