475495-70-6Relevant academic research and scientific papers
Tunable chiral monophosphines as ligands in enantioselective rhodium-catalyzed ring-opening of oxabenzonorbornadienes with amines
Luo, Renshi,Xie, Ling,Liao, Jianhua,Xin, Hu,Chan, Albert S.C.
, p. 709 - 717 (2014/06/09)
A new tunable chiral monophosphine was used as a ligand for asymmetric rhodium-catalyzed ring-opening of oxabenzonorbornadiene with amines, providing a series of chiral ring-opened products in high yields (up to 97%) and with high enantioselectivities (>99%).The reaction can be performed at rt to obtain the desired product with high enantioselectivity.
Asymmetric ring-opening of oxabenzonorbornadiene with amines promoted by a chiral iridium-monophosphine catalyst
Luo, Renshi,Liao, Jianhua,Xie, Ling,Tang, Wenjun,Chan, Albert S. C.
supporting information, p. 9959 - 9961 (2013/10/22)
A new iridium-monophosphine catalyst is found to be efficient for asymmetric ring-opening of benzonorbornadiene with amines, providing a series of chiral substituted dihydronaphthalenes in high yields (up to 98%) and excellent enantioselectivities (>99%).
Rhodium-catalyzed asymmetric ring-opening reactions of N-Boc-azabenzonorbornadiene with N-substituted piperazine nucleophiles
Long, Yuhua,Yang, Dingqiao,Zeng, Heping,Xie, Lei,Wu, Lihuan,Mo, Haihong,Zuo, Xiongjun
scheme or table, p. 235 - 242 (2010/11/02)
Asymmetric ring-opening reactions of N-Boc-azabenzonorbornadiene with N-substituted piperazine nucleophilesin the presence of 5 mol% of [Rh(COD)Cl]2 and 10 mol% of chiral ligand, (R,S)-PPF-P-t-Bu2, gave the corresponding1,2-diamine p
Iridium-catalyzed asymmetric ring opening of azabicyclic alkenes by amines
Long, Yuhua,Yang, Dingqiao,Zhang, Zhenming,Wu, Yujuan,Zeng, Heping,Chen, Yu
experimental part, p. 7291 - 7299 (2011/01/12)
The enantioselective ring-opening reactions of azabicyclic alkenes with primary and secondary aromatic amine nucleophiles are reported using an iridium catalyst generated in situ from 1.5 mol % of [Ir(COD)Cl]2 and 3 mol % of (S)-BINAP. The reac
Iridium-catalyzed asymmetric ring-opening reactions of N-boc- azabenzonorbornadiene with secondary amine nucleophiles
Yang, Dingqiao,Long, Yuhua,Wang, Huan,Zhang, Zhenming
supporting information; experimental part, p. 4723 - 4726 (2009/05/31)
(Equation Presented) Iridium-catalyzed asymmetric ring-opening reactions of N-Boc-azabenzonorbornadiene with a number of secondary amines has been developed for the first time. The reaction gave 1,2-trans-diamine derivatives in moderate to good yields wit
Rhodium-catalyzed ring-opening reactions of N-boc-azabenzonorbornadienes with amine nucleophiles
Cho, Yong-Hwan,Zunic, Valentin,Senboku, Hisanori,Olsen, Madeline,Lautens, Mark
, p. 6837 - 6846 (2007/10/03)
In the presence of a rhodium catalyst (5 mol %) generated in situ from [Rh(cod)Cl]2 and (S, S′)-(R, R′)-C2-ferriphos (4a), the asymmetric ring-opening reaction of azabenzonorbornadienes (1a-m) with various aliphatic and aromatic amin
An expedient enantioselective route to diaminotetralins: application in the preparation of analgesic compounds.
Lautens, Mark,Fagnou, Keith,Zunic, Valentin
, p. 3465 - 3468 (2007/10/03)
Advances to the rhodium-catalyzed asymmetric ring-opening protocol have allowed this methodology to be extended to azabicyclic alkenes, the first time that rhodium has been used in allylic functionalizations with nitrogen leaving groups. The product diami
