475495-79-5

Upstream product

• 475495-70-6 (1S,2S)-[2-(4-phenyl-piperazin-1-yl)-1,2-dihydro-naphthalen-1-yl]-carbamic acid tert-butyl ester 
• 92-54-6 4-phenyl-1-piperazine 

Relevant academic research and scientific papers

Rhodium-catalyzed ring-opening reactions of N-boc-azabenzonorbornadienes with amine nucleophiles

In the presence of a rhodium catalyst (5 mol %) generated in situ from [Rh(cod)Cl]2 and (S, S′)-(R, R′)-C2-ferriphos (4a), the asymmetric ring-opening reaction of azabenzonorbornadienes (1a-m) with various aliphatic and aromatic amin

An expedient enantioselective route to diaminotetralins: application in the preparation of analgesic compounds.

Advances to the rhodium-catalyzed asymmetric ring-opening protocol have allowed this methodology to be extended to azabicyclic alkenes, the first time that rhodium has been used in allylic functionalizations with nitrogen leaving groups. The product diami