475571-47-2

Usage

Chemical compound

2,5-Pyridinedione, 1,6-dihydro-3,4-bis(hydroxymethyl)-6-methoxy-6-methyl(9CI)

Uses

Synthesis of pharmaceutical drugs
Derivative of pyridine

Characteristics

Dihydroand hydroxymethyl substituents
Precursor in the production of medications
Important component in the pharmaceutical industry
Research reagent in laboratories for studies and experiments

Upstream product

• 58-56-0 pyridoxal hydrochloride 
• 67-56-1 methanol 

Relevant academic research and scientific papers

Novel ring chemistry of vitamin B6 with singlet oxygen and an activated ene: Isolated products and identified intermediates suggesting an operable [3 + 2] cycloaddition

Pyridoxine reaction with 1O2 in aqueous solution at neutral pH resulted in oxidation at the 2- and 6-positions of the pyridine ring and unprecedented ring contraction. Kinetic and low temperature studies provided observable intermediates by NMR spectroscopy. In addition, novel cycloaddition between pyridoxine and N-methylmaleimide, without N-alkylation and in water, suggest a common [3 + 2] cycloaddition with the 3-hydroxypyridine ring.