475994-60-6

Basic information

• Product Name: 8-BROMO-2H-ISOQUINOLIN-1-ONE
• Synonyms: 8-BROMO-2H-ISOQUINOLIN-1-ONE;8-Bromoisoquinolin-1(2H)-one;8-BroMo-2H-isoquinoline-1-one;8-Bromo-1(2H)-isoquinolinone;8-Bromoisoquinolin-1-ol;8-Bromo-1-hydroxyisoquinoline;8-Bromoisoquinolin-1(2H);8-bromo-1(2H)-isoquinolin-1-one
• CAS NO: 475994-60-6
• Molecular Formula: C₉H₆BrNO
• Molecular Weight: 224.056
• Mol File: 475994-60-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 446.078°C at 760 mmHg
• Flash Point: 223.58°C
• Appearance: /
• Density: 1.620±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.63
• Storage Temp.: 2-8°C
• PKA: 11.81±0.20(Predicted)
• CAS DataBase Reference: 8-BROMO-2H-ISOQUINOLIN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-BROMO-2H-ISOQUINOLIN-1-ONE(475994-60-6)
• EPA Substance Registry System: 8-BROMO-2H-ISOQUINOLIN-1-ONE(475994-60-6)

Safety Data

• Hazardous Substances Data: 475994-60-6(Hazardous Substances Data)

Usage

General Description

8-Bromo-2H-isoquinolin-1-one, also known as 8-bromoisoquinolin-1-one, is a chemical compound with the molecular formula C9H6BrNO. It is a yellow powder that is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also known for its use in research and as a precursor in the synthesis of fluorescent dyes and biologically active compounds. This chemical compound is known for its strong fluorescence, making it a valuable ingredient in fluorescent labeling and imaging applications. Additionally, it has attracted attention for its potential biological activities and is under investigation for its potential use as an antiviral and antifungal agent.

InChI:InChI=1/C9H6BrNO/c10-7-3-1-2-6-4-5-11-9(12)8(6)7/h1-5H,(H,11,12)

Upstream product

• 405161-29-7 (2-bromobenzylidene)(2,2-dimethoxyethyl)amine 
• 475994-58-2 8-bromo-2-oxidoisoquinolin-2-ium 
• 6630-33-7 ortho-bromobenzaldehyde 
• 63927-22-0 8-bromo-isoquinoline 

Downstream Products

• 491-30-5 1-isoquinolone 
• 1072157-19-7 8-(2,6-dimethylphenylamino)-2H-isoquinolin-1-one 
• 643069-17-4 8-bromo-2-methylisoquinolin-1(2H)-one 
• 1233025-78-9 8-bromo-1-chloro-isoquinoline 

Relevant articles and documents

TRICYCLIC DEGRADERS OF IKAROS AND AIOLOS

Tricyclic cereblon binders for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway for therapeutic applications are described.

ANTIBACTERIAL COMPOUNDS

Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man