476310-80-2Relevant academic research and scientific papers
Enantioselective acylation of (±)-cis-flavan-4-ols catalyzed by lipase from Candida cylindracea (CCL) and the synthesis of enantiopure flavan-4-ones
Ramadas, Sathunuru,Krupadanam, G.L. David
, p. 3381 - 3391 (2007/10/03)
Lipase Candida cylindracea (CCL) catalyzed acylation of (±)-cis-flavan-4-ols using vinyl acetate as the acyldonor in DME-toluene (1:2) gave (-)-(2R,4R)-4-acetoxyflavans 9a-m and (+)-(2S,4S)-flavan-4-ols 10a-m in high enantiomeric excess. (+)-(2S,4S)-Flava
Lipase-catalyzed kinetic resolution of (+/-)-cis-flavan-4-ol and its acetate: synthesis of chiral 3-hydroxyflavanones.
Todoroki, Tamotsu,Saito, Akiko,Tanaka, Akira
, p. 1772 - 1774 (2007/10/03)
Lipase-catalyzed kinetic resolution of (+/-)-cis-flavan-4-ol and its acetate led to enantiomerically enriched flavan-4-ol and its acetate. These chiral compounds were converted to (2R, 3R)- and (25, 3S)-3-hydroxyflavanones.
Enzymatic Kinetic Resolution of Flavanone and cis-4-Acetoxyflavan
Izumi, Taeko,Hino, Toshimi,Kasahara, Akira
, p. 1265 - 1268 (2007/10/02)
The microbial, asymmetric reduction of flavanone with fermenting bakers' yeast led to the formation of (2S,4S)-(+)-cis-4-hydroxyflavan and (2R)-(+)-flavanone.The kinetic resolution of racemic cis-4-acetoxyflavan with lipase PS yields (2R,4R)-(-)-cis-4-hydroxyflavan, and the (2S,4S)-(+)-enantiomer remains as the acetate.
